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ENZYME

ENZYME entry: EC 4.2.1.150

Accepted Name
short-chain-enoyl-CoA hydratase
Alternative Name(s)
3-hydroxybutyryl-CoA dehydratase
crotonase
Reaction catalysed
a short-chain (3S)-3-hydroxyacyl-CoA <=> a short-chain (2E)-enoyl-CoA + H2O
Comment(s)
  • The enzyme from the bacterium Clostridium acetobutylicum is part of the central fermentation pathway and plays a key role in the production of both acids and solvents.
  • It is specific for short, C4-C6, chain length substrates and exhibits an extremely high turnover number for crotonyl-CoA. cf. EC 4.2.1.17 and EC 4.2.1.74.
Cross-references
BRENDA4.2.1.150
EC2PDB4.2.1.150
ExplorEnz4.2.1.150
PRIAM enzyme-specific profiles4.2.1.150
KEGG Ligand Database for Enzyme Nomenclature4.2.1.150
IUBMB Enzyme Nomenclature4.2.1.150
IntEnz4.2.1.150
MEDLINEFind literature relating to 4.2.1.150
MetaCyc4.2.1.150
Rhea expert-curated reactions4.2.1.150
UniProtKB/Swiss-Prot
Q0AVM1, CRCH_SYNWWP52046, CRT_CLOABP45361, CRT_CLODI
P81357, CRT_CLOPA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-