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ENZYME entry: EC 4.2.1.177

Accepted Name
(2S)-3-sulfopropanediol dehydratase.
Alternative Name(s)
(S)-DHPS dehydratase.
Reaction catalysed
(2S)-2,3-dihydroxypropane-1-sulfonate <=> 3-oxopropane-1-sulfonate + H(2)O
Comment(s)
  • The enzyme, characterized from the bacterium Klebsiella oxytoca, participates in (2S)-2,3-dihydroxypropane-1-sulfonate degradation.
  • The active form of the enzyme contains a glycyl radical that is generated by a dedicated activating enzyme via chemistry involving S-adenosyl-L-methionine (AdoMet) and a [4Fe-4S] cluster.
Cross-references
BRENDA4.2.1.177
EC2PDB4.2.1.177
ExplorEnz4.2.1.177
PRIAM enzyme-specific profiles4.2.1.177
KEGG Ligand Database for Enzyme Nomenclature4.2.1.177
IUBMB Enzyme Nomenclature4.2.1.177
IntEnz4.2.1.177
MEDLINEFind literature relating to 4.2.1.177
MetaCyc4.2.1.177
Rhea expert-curated reactions4.2.1.177

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-