ENZYME entry: EC 4.2.1.22
| Accepted Name |
|---|
| Cystathionine beta-synthase.
|
| Alternative Name(s) |
|---|
| Beta-thionase. |
| Methylcysteine synthase. |
| Serine sulfhydrase. |
| Reaction catalysed |
|---|
| L-serine + L-homocysteine <=> L-cystathionine + H(2)O |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- A multifunctional enzyme: catalyzes beta-replacement reaction between
L-serine, L-cysteine, cysteine thioethers or some other beta-
substituted alpha-L-amino acids and a variety of mercaptans.
- Formerly EC 4.2.1.21.
|
| Cross-references |
|---|
| PROSITE | PDOC00700 |
| BRENDA | 4.2.1.22 |
| EC2PDB | 4.2.1.22 |
| ExplorEnz | 4.2.1.22 |
| PRIAM enzyme-specific profiles | 4.2.1.22 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.2.1.22 |
| IUBMB Enzyme Nomenclature | 4.2.1.22 |
| IntEnz | 4.2.1.22 |
| MEDLINE | Find literature relating to 4.2.1.22 |
| MetaCyc | 4.2.1.22 |
| UniProtKB/Swiss-Prot |
| P0DN79, CBSL_HUMAN; | P46794, CBS_DICDI; | P35520, CBS_HUMAN; |
| Q58H57, CBS_MACFA; | Q91WT9, CBS_MOUSE; | Q9N0V7, CBS_RABIT; |
| P32232, CBS_RAT; | P32582, CBS_YEAST; | Q9YBL2, CYSO_AERPE; |
| P9WP50, Y1077_MYCTO; | P9WP51, Y1077_MYCTU; |
|
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