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ENZYME

ENZYME entry: EC 4.2.1.22

PURL: https://purl.expasy.org/enzyme/EC/4.2.1.22
Accepted Name
cystathionine beta-synthase
Alternative Name(s)
beta-thionase
methylcysteine synthase
serine sulfhydrase
Reaction catalysed
L-homocysteine + L-serine = L,L-cystathionine + H2O
Comment(s)
  • A multifunctional enzyme: catalyzes beta-replacement reaction between L-serine, L-cysteine, cysteine thioethers or some other beta- substituted alpha-L-amino acids and a variety of mercaptans.
  • Formerly EC 4.2.1.21.
Cross-references
BRENDA4.2.1.22
EC2PDB4.2.1.22
ExplorEnz4.2.1.22
KEGG Ligand Database for Enzyme Nomenclature4.2.1.22
IUBMB Enzyme Nomenclature4.2.1.22
MEDLINEFind literature relating to 4.2.1.22
MetaCyc4.2.1.22
Rhea expert-curated reactions4.2.1.22
UniProtKB/Swiss-Prot
G5EFH8, CBS1_CAEELQ9N4K2, CBS2_CAEELQ2V0C9, CBS_APIME
P46794, CBS_DICDIP35520, CBS_HUMANQ58H57, CBS_MACFA
Q91WT9, CBS_MOUSEQ9N0V7, CBS_RABITP32232, CBS_RAT
P32582, CBS_YEASTQ9YBL2, CYSO_AERPEP9WP50, Y1077_MYCTO
P9WP51, Y1077_MYCTU

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-