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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Acetylenecarboxylate hydratase.
Alternative Name(s)
Acetylenemonocarboxylate hydratase.
Alkynoate hydratase.
Malonate-semialdehyde dehydratase.
Reaction catalysed
3-oxopropanoate <=> propynoate + H(2)O
  • The reaction is effectively irreversible, favoring oxopropanoate (malonic semialdehyde) and its tautomers.
  • Also acts on but-3-ynoate forming acetoacetate.
  • The mechanism appears to involve hydration of the acetylene to 3-hydroxypropenoate, which will spontaneously tautomerize to 3-oxopropanoate.
  • It is thus analogous to EC in its mechanism.
  • Formerly EC
PRIAM enzyme-specific profiles4.2.1.27
KEGG Ligand Database for Enzyme Nomenclature4.2.1.27
IUBMB Enzyme Nomenclature4.2.1.27
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