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ENZYME

ENZYME entry: EC 4.2.1.3

Accepted Name
aconitate hydratase
Alternative Name(s)
aconitase
cis-aconitase
citrate(isocitrate) hydro-lyase
citrate hydro-lyase
Reaction catalysed
citrate <=> D-threo-isocitrate
Comment(s)
  • Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.
  • The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.
  • cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.
  • Formerly EC 4.2.1.4.
Cross-references
BRENDA4.2.1.3
EC2PDB4.2.1.3
ExplorEnz4.2.1.3
PRIAM enzyme-specific profiles4.2.1.3
KEGG Ligand Database for Enzyme Nomenclature4.2.1.3
IUBMB Enzyme Nomenclature4.2.1.3
IntEnz4.2.1.3
MEDLINEFind literature relating to 4.2.1.3
MetaCyc4.2.1.3
Rhea expert-curated reactions4.2.1.3
UniProtKB/Swiss-Prot
P09339, ACNA_BACSUP70920, ACNA_BRADUQ6NH63, ACNA_CORDI
Q8FTA8, ACNA_COREFQ8NQ98, ACNA_CORGLQ4JVM4, ACNA_CORJK
Q937N8, ACNA_CUPNEQ9RTN7, ACNA_DEIRAP25516, ACNA_ECOLI
Q2A1K3, ACNA_FRATHO08451, ACNA_MYCAVA0QX20, ACNA_MYCS2
O53166, ACNA_MYCTUQ9I3F5, ACNA_PSEAEQ1RKD5, ACNA_RICBR
Q92G90, ACNA_RICCNQ4UK20, ACNA_RICFEQ9ZCF4, ACNA_RICPR
Q68VV0, ACNA_RICTYQ8ZP52, ACNA_SALTYQ5HG69, ACNA_STAAC
P63433, ACNA_STAAMP99148, ACNA_STAANQ6GH55, ACNA_STAAR
Q6G9K9, ACNA_STAASP63434, ACNA_STAAWQ5HPJ0, ACNA_STAEQ
Q8CPC2, ACNA_STAESQ59938, ACNA_STRMUQ5SMF6, ACNA_THET8
P36683, ACNB_ECOLIQ9ZL64, ACNB_HELPJP56418, ACNB_HELPY
Q9I2V5, ACNB_PSEAEQ8ZRS8, ACNB_SALTYP74582, ACNB_SYNY3
Q8EJW3, ACND_SHEONQ42560, ACO1_ARATHQ94A28, ACO2M_ARATH
Q9SIB9, ACO3M_ARATHQ0VCU1, ACOHC_BOVINQ23500, ACOHC_CAEEL
Q90875, ACOHC_CHICKP49608, ACOHC_CUCMAQ42669, ACOHC_CUCMC
Q54X73, ACOHC_DICDIP21399, ACOHC_HUMANP28271, ACOHC_MOUSE
Q6YZX6, ACOHC_ORYSJQ01059, ACOHC_RABITQ63270, ACOHC_RAT
O04916, ACOHC_SOLTUD4AT77, ACON_ARTBCQ4WLN1, ACON_ASPFU
P20004, ACON_BOVINP34455, ACON_CAEELP82611, ACON_CANAL
Q54XS2, ACON_DICDIC8VG90, ACON_EMENIP49609, ACON_GRAGA
Q99798, ACON_HUMANP37032, ACON_LEGPHQ99KI0, ACON_MOUSE
P16276, ACON_PIGQ9ER34, ACON_RATO13966, ACON_SCHPO
P19414, ACON_YEASTQ8NSL3, PRPD2_CORGLQ937N6, PRPD_CUPNE
Q8X693, PRPD_ECO57P77243, PRPD_ECOLIH8F0D6, PRPD_MYCTE
O06582, PRPD_MYCTUQ8Z903, PRPD_SALTIP74840, PRPD_SALTY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-