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ENZYME

ENZYME entry: EC 4.2.1.75

PURL: https://purl.expasy.org/enzyme/EC/4.2.1.75
Accepted Name
uroporphyrinogen-III synthase
Alternative Name(s)
hydroxymethylbilane hydro-lyase (cyclizing)
uroporphyrinogen-III cosynthase
uroporphyrinogen-III cosynthetase
Reaction catalysed
hydroxymethylbilane = uroporphyrinogen III + H2O
Comment(s)
In the presence of EC 2.5.1.61, forms uroporphyrinogen III from porphobilinogen.
Cross-references
BRENDA4.2.1.75
EC2PDB4.2.1.75
ExplorEnz4.2.1.75
KEGG Ligand Database for Enzyme Nomenclature4.2.1.75
IUBMB Enzyme Nomenclature4.2.1.75
MEDLINEFind literature relating to 4.2.1.75
MetaCyc4.2.1.75
Rhea expert-curated reactions4.2.1.75
UniProtKB/Swiss-Prot
O48721, HEM4_ARATHO30120, HEM4_ARCFUP21248, HEM4_BACSU
Q59335, HEM4_CHLP8Q8KCJ3, HEM4_CHLTEP09126, HEM4_ECOLI
P10746, HEM4_HUMANQ58401, HEM4_METJAO26268, HEM4_METTH
P51163, HEM4_MOUSEQ10QR9, HEM4_ORYSJQ59683, HEM4_PROMI
P48246, HEM4_PSEAEQ59294, HEM4_RUMJOQ9L6Q3, HEM4_SALTY
P87214, HEM4_SCHPOP42452, HEM4_SYNE7P06174, HEM4_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-