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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 4.2.1.84

Accepted Name
Nitrile hydratase.
Alternative Name(s)
Nitrilase.
Nitrile hydro-lyase.
Reaction catalysed
An aliphatic amide <=> a nitrile + H(2)O
Comment(s)
  • Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides.
  • Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).
Cross-references
BRENDA4.2.1.84
EC2PDB4.2.1.84
ExplorEnz4.2.1.84
PRIAM enzyme-specific profiles4.2.1.84
KEGG Ligand Database for Enzyme Nomenclature4.2.1.84
IUBMB Enzyme Nomenclature4.2.1.84
IntEnz4.2.1.84
MEDLINEFind literature relating to 4.2.1.84
MetaCyc4.2.1.84
UniProtKB/Swiss-Prot
P21219, NHA1_RHORH;  P29378, NHA2_RHORH;  A9V2C1, NHAAB_MONBE;  
P27764, NHAA_PSECL;  P97051, NHAA_PSEPU;  Q7SID2, NHAA_PSETH;  
P13448, NHAA_RHOER;  Q53118, NHAA_RHOSO;  P27763, NHAB_PSECL;  
P97052, NHAB_PSEPU;  Q7SID3, NHAB_PSETH;  P13449, NHAB_RHOER;  
Q53117, NHAB_RHOSO;  P21220, NHB1_RHORH;  P29379, NHB2_RHORH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-