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ENZYME entry: EC 4.2.2.3
| Accepted Name |
|---|
| Mannuronate-specific alginate lyase.
|
| Alternative Name(s) |
|---|
| Alginate lyase I. |
| Poly(beta-D-mannuronate) lyase. |
| Poly(mana) alginate lyase. |
| Reaction catalysed |
|---|
| Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end |
| Comment(s) |
|---|
- The enzyme catalyzes the degradation of alginate by a beta-
elimination reaction.
- It cleaves the (1->4) bond between beta-D-mannuronate and either
alpha-L-guluronate or beta-D-mannuronate, generating oligosaccharides
with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-
reducing ends and beta-D-mannuronate at the reducing end.
- Depending on the composition of the substrate, the enzyme produces
oligosaccharides ranging from two to four residues, with preference
for shorter products.
- Cf. EC 4.2.2.11.
- Formerly EC 4.2.99.4.
|
| Cross-references |
|---|
| BRENDA | 4.2.2.3 |
| EC2PDB | 4.2.2.3 |
| ExplorEnz | 4.2.2.3 |
| PRIAM enzyme-specific profiles | 4.2.2.3 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.2.2.3 |
| IUBMB Enzyme Nomenclature | 4.2.2.3 |
| IntEnz | 4.2.2.3 |
| MEDLINE | Find literature relating to 4.2.2.3 |
| MetaCyc | 4.2.2.3 |
| UniProtKB/Swiss-Prot |
| Q9ZFG9, ALGE7_AZOVI; | O50660, ALGL_AZOCH; | C1DP89, ALGL_AZOVD; |
| O52195, ALGL_AZOVI; | Q9ZNB7, ALGL_COBMA; | A6V1P7, ALGL_PSEA7; |
| B7UUU9, ALGL_PSEA8; | Q02R18, ALGL_PSEAB; | Q06749, ALGL_PSEAE; |
| Q1I563, ALGL_PSEE4; | Q4KHY5, ALGL_PSEF5; | P59786, ALGL_PSEFL; |
| C3KDZ3, ALGL_PSEFS; | A5W8V4, ALGL_PSEP1; | Q3KHR0, ALGL_PSEPF; |
| B0KGQ9, ALGL_PSEPG; | Q88ND1, ALGL_PSEPK; | B1J479, ALGL_PSEPW; |
| Q887Q5, ALGL_PSESM; | Q9L7P2, ALGL_PSESY; | Q4ZXL0, ALGL_PSEU2; |
| P39049, ALXM_PHOS4; | Q59478, ALYA_KLEPN; | Q59639, ALYA_PSEAL; |
| Q06365, ALYP_PSESO; | B2FHL8, PL_STRMK; |
|
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All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-