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ENZYME entry: EC 4.2.3.151

Accepted Name
Pentamethylcyclopentadecatrienol synthase.
Reaction catalysed
Geranylgeranyl diphosphate + H(2)O <=> (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate
Cofactor(s)
Iron-sulfur; Mg(2+).
Comment(s)
  • Isolated from the bacterium Streptomyces sp. SANK 60404.
  • This trifunctional enzyme also produces (R)-nephthenol and (R)- cembrene A (cf. EC 4.2.3.149 and EC 4.2.3.150).
Cross-references
BRENDA4.2.3.151
EC2PDB4.2.3.151
ExplorEnz4.2.3.151
PRIAM enzyme-specific profiles4.2.3.151
KEGG Ligand Database for Enzyme Nomenclature4.2.3.151
IUBMB Enzyme Nomenclature4.2.3.151
IntEnz4.2.3.151
MEDLINEFind literature relating to 4.2.3.151
MetaCyc4.2.3.151
Rhea expert-curated reactions4.2.3.151
UniProtKB/Swiss-Prot
M1VDX3, DTCYB_STRSQ

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