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ENZYME entry: EC 4.2.3.149
Accepted Name |
nephthenol synthase.
|
Reaction catalysed |
(2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (R)-nephthenol + diphosphate |
Comment(s) |
- Two isozymes with this activity were isolated from the bacterium
Streptomyces sp. SANK 60404.
- The enzyme encoded by the DtcycA gene also produces cembrene C (see
4.2.3.148), while the enzyme encoded by the DtcycB gene also produces
(R)-cembrene A and (1S,4E,8E,12E)-2,2,5,9,13-
pentamethylcyclopentadeca-4,8,12-trien-1-ol (cf. EC 4.2.3.150 and
EC 4.2.3.151).
|
Cross-references |
BRENDA | 4.2.3.149 |
EC2PDB | 4.2.3.149 |
ExplorEnz | 4.2.3.149 |
PRIAM enzyme-specific profiles | 4.2.3.149 |
KEGG Ligand Database for Enzyme Nomenclature | 4.2.3.149 |
IUBMB Enzyme Nomenclature | 4.2.3.149 |
IntEnz | 4.2.3.149 |
MEDLINE | Find literature relating to 4.2.3.149 |
MetaCyc | 4.2.3.149 |
Rhea expert-curated reactions | 4.2.3.149 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
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