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ENZYME entry: EC 4.2.3.203

Accepted Name
Isoelisabethatriene synthase.
Reaction catalysed
Geranylgeranyl diphosphate <=> isoelisabethatriene + diphosphate
Comment(s)
  • Isolated from the bacterium Streptomyces clavuligerus.
  • The 1-proR hydrogen atom of geranylgeranyl diphosphate is involved in a 1,3-hydride shift to the side-chain.
  • The enzyme also produces hydropyrene, hydropyrenol, and traces of other diterpenoids.
  • Cf. EC 4.2.3.201 and EC 4.2.3.202.
Cross-references
BRENDA4.2.3.203
EC2PDB4.2.3.203
ExplorEnz4.2.3.203
PRIAM enzyme-specific profiles4.2.3.203
KEGG Ligand Database for Enzyme Nomenclature4.2.3.203
IUBMB Enzyme Nomenclature4.2.3.203
IntEnz4.2.3.203
MEDLINEFind literature relating to 4.2.3.203
MetaCyc4.2.3.203

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-