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ENZYME entry: EC 4.2.3.77

Accepted Name
(+)-germacrene D synthase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate <=> (+)-germacrene D + diphosphate
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
The formation of (+)-germacrene D involves a 1,2-hydride shift whereas for (-)-germacrene D there is a 1,3-hydride shift (see EC 4.2.3.75).
Cross-references
BRENDA4.2.3.77
EC2PDB4.2.3.77
ExplorEnz4.2.3.77
PRIAM enzyme-specific profiles4.2.3.77
KEGG Ligand Database for Enzyme Nomenclature4.2.3.77
IUBMB Enzyme Nomenclature4.2.3.77
IntEnz4.2.3.77
MEDLINEFind literature relating to 4.2.3.77
MetaCyc4.2.3.77
Rhea expert-curated reactions4.2.3.77
UniProtKB/Swiss-Prot
Q2NM15, FARS_MAIZE;  D8RLD3, MTS17_SELML;  Q29VN3, TPS8_MAIZE;  
Q0VHD6, TSGD1_ZINOF;  

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