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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 4.2.3.87

Accepted Name
Alpha-guaiene synthase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate <=> alpha-guaiene + diphosphate
Cofactor(s)
Mg(2+).
Comment(s)
  • The enzyme from Pogostemon cablin gives 13% alpha-guaiene as well as 37% (-)-patchoulol (see EC 4.2.3.70), 13% delta-guaiene (see EC 4.2.3.93), and traces of at least ten other sesquiterpenoids.
  • In Aquilaria crassna three clones of the enzyme gave about 80% delta- guaiene and 20% alpha-guaiene, with traces of alpha-humulene.
  • A fourth clone gave 54% delta-guaiene and 45% alpha-guaiene.
Cross-references
BRENDA4.2.3.87
EC2PDB4.2.3.87
ExplorEnz4.2.3.87
PRIAM enzyme-specific profiles4.2.3.87
KEGG Ligand Database for Enzyme Nomenclature4.2.3.87
IUBMB Enzyme Nomenclature4.2.3.87
IntEnz4.2.3.87
MEDLINEFind literature relating to 4.2.3.87
MetaCyc4.2.3.87
UniProtKB/Swiss-Prot
D0VMR6, DGUS1_AQUCR;  D0VMR7, DGUS2_AQUCR;  D0VMR8, DGUS3_AQUCR;  
Q49SP3, TPSPS_POGCB;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-