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ENZYME entry: EC 4.2.3.93

Accepted Name
Delta-guaiene synthase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate <=> delta-guaiene + diphosphate
Cofactor(s)
Mg(2+).
Comment(s)
  • In Aquilaria crassna three clones of the enzyme gave about 80% delta- guaiene and 20% alpha-guaiene (see also EC 4.2.3.87).
  • A fourth clone gave 54% delta-guaiene and 45% alpha-guaiene.
  • The enzyme from Pogostemon cablin gives 13% delta-guaiene as well as 37% (-)-patchoulol (see EC 4.2.3.70), 13% alpha-guaiene (see EC 4.2.3.87), and traces of at least ten other sesquiterpenoids.
Cross-references
BRENDA4.2.3.93
EC2PDB4.2.3.93
ExplorEnz4.2.3.93
PRIAM enzyme-specific profiles4.2.3.93
KEGG Ligand Database for Enzyme Nomenclature4.2.3.93
IUBMB Enzyme Nomenclature4.2.3.93
IntEnz4.2.3.93
MEDLINEFind literature relating to 4.2.3.93
MetaCyc4.2.3.93
UniProtKB/Swiss-Prot
D0VMR6, DGUS1_AQUCR;  D0VMR7, DGUS2_AQUCR;  D0VMR8, DGUS3_AQUCR;  
Q49SP3, TPSPS_POGCB;  

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