A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 4.3.1.23
| Accepted Name |
|---|
| Tyrosine ammonia-lyase.
|
| Alternative Name(s) |
|---|
| L-tyrosine ammonia-lyase. |
| TAL. |
| Tyrase. |
| Reaction catalysed |
|---|
| L-tyrosine <=> trans-p-hydroxycinnamate + ammonia |
| Cofactor(s) |
|---|
| MIO.
|
| Comment(s) |
|---|
- Member of the aromatic amino acid lyase family, other members of
which are EC 4.3.1.3, EC 4.3.1.24 and EC 4.3.1.25.
- Far more active with tyrosine than with phenylalanine as substrate,
but the substrate specificity can be switched by mutation of a single
amino acid (H89F) in the enzyme from the bacterium Rhodobacter
sphaeroides.
- Formerly EC 4.3.1.5.
|
| Cross-references |
|---|
| PROSITE | PDOC00424 |
| BRENDA | 4.3.1.23 |
| EC2PDB | 4.3.1.23 |
| ExplorEnz | 4.3.1.23 |
| PRIAM enzyme-specific profiles | 4.3.1.23 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.3.1.23 |
| IUBMB Enzyme Nomenclature | 4.3.1.23 |
| IntEnz | 4.3.1.23 |
| MEDLINE | Find literature relating to 4.3.1.23 |
| MetaCyc | 4.3.1.23 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.3.1.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-