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ENZYME

ENZYME entry: EC 4.3.2.2

Accepted Name
adenylosuccinate lyase
Alternative Name(s)
adenylosuccinase
succino AMP-lyase
Reaction catalysed
  • N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP
  • (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate
Comment(s)
Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole.
Cross-references
BRENDA4.3.2.2
EC2PDB4.3.2.2
ExplorEnz4.3.2.2
PRIAM enzyme-specific profiles4.3.2.2
KEGG Ligand Database for Enzyme Nomenclature4.3.2.2
IUBMB Enzyme Nomenclature4.3.2.2
IntEnz4.3.2.2
MEDLINEFind literature relating to 4.3.2.2
MetaCyc4.3.2.2
Rhea expert-curated reactions4.3.2.2
UniProtKB/Swiss-Prot
O66856, PUR8_AQUAEO28041, PUR8_ARCFUP12047, PUR8_BACSU
A3KN12, PUR8_BOVINP57351, PUR8_BUCAIQ8K9Q7, PUR8_BUCAP
Q89AM3, PUR8_BUCBPQ60Q90, PUR8_CAEBRQ21774, PUR8_CAEEL
P21265, PUR8_CHICKQ9RSE6, PUR8_DEIRAQ54J34, PUR8_DICDI
P0AB90, PUR8_ECOL6P0AB89, PUR8_ECOLIP44797, PUR8_HAEIN
Q9ZKA2, PUR8_HELPJP56468, PUR8_HELPYP30566, PUR8_HUMAN
A5IGB3, PUR8_LEGPCQ5ZXD1, PUR8_LEGPHQ8HXY5, PUR8_MACFA
Q58339, PUR8_METJAO27580, PUR8_METTHP54822, PUR8_MOUSE
Q9I0K9, PUR8_PSEAEQ9UZ99, PUR8_PYRABO58582, PUR8_PYRHO
G4VQX9, PUR8_SCHMAO60105, PUR8_SCHPOP52201, PUR8_SPICI
Q2FFI7, PUR8_STAA3Q2G2S0, PUR8_STAA8Q2YU66, PUR8_STAAB
Q5HEL4, PUR8_STAACQ99SX9, PUR8_STAAMQ7A4Q3, PUR8_STAAN
Q6GFE9, PUR8_STAARQ6G825, PUR8_STAASQ7A0G9, PUR8_STAAW
Q5HN26, PUR8_STAEQQ8CRT6, PUR8_STAESQ4L7M3, PUR8_STAHJ
Q49YV3, PUR8_STAS1P72478, PUR8_STRMUP74384, PUR8_SYNY3
Q9X0I0, PUR8_THEMAA0A0H3AL67, PUR8_VIBC3Q05911, PUR8_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-