ENZYME entry: EC 4.3.2.9
Accepted Name |
Gamma-glutamylcyclotransferase.
|
Alternative Name(s) |
GGCT. |
Reaction catalysed |
Alpha-(gamma-L-glutamyl)-L-amino acid <=> alpha-L-amino acid + 5-oxo-L-proline |
Comment(s) |
- The enzyme, found in animals and plants, acts on derivatives of
L-glutamate, L-2-aminobutanoate, L-alanine and glycine.
- The enzyme acts as a cyclotransferase, cleaving the amide bond via
transamidation using the alpha-amine of the L-glutamyl residue,
releasing it as the cyclic 5-oxo-L-proline.
- Formerly EC 2.3.2.4.
|
Cross-references |
BRENDA | 4.3.2.9 |
EC2PDB | 4.3.2.9 |
ExplorEnz | 4.3.2.9 |
PRIAM enzyme-specific profiles | 4.3.2.9 |
KEGG Ligand Database for Enzyme Nomenclature | 4.3.2.9 |
IUBMB Enzyme Nomenclature | 4.3.2.9 |
IntEnz | 4.3.2.9 |
MEDLINE | Find literature relating to 4.3.2.9 |
MetaCyc | 4.3.2.9 |
UniProtKB/Swiss-Prot |
Q2UPC2, ACLK_ASPOR; | Q8GY54, GCT21_ARATH; | Q84MC1, GCT22_ARATH; |
Q84QC1, GCT23_ARATH; | Q32LE4, GGCT_BOVIN; | O75223, GGCT_HUMAN; |
Q9D7X8, GGCT_MOUSE; | E9R9Y3, GLIK_ASPFU; | M1W855, TCPK_CLAP2; |
A0A1U9YI11, VERK_CLORO; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-