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ENZYME

ENZYME entry: EC 4.4.1.16

PURL: https://purl.expasy.org/enzyme/EC/4.4.1.16
Accepted Name
selenocysteine lyase
Alternative Name(s)
selenocysteine beta-lyase
selenocysteine reductase
Reaction catalysed
L-selenocysteine + AH2 = hydrogenselenide + L-alanine + A + H(+)
Comment(s)
  • Dithiothreitol or 2-sulfanylethan-1-ol (2-mercaptoethanol) can act as the reducing agent in the reaction.
  • The enzyme from animals does not act on cysteine, serine or chloroalanine, while the enzyme from bacteria shows activity with cysteine (cf. EC 2.8.1.7).
Cross-references
BRENDA4.4.1.16
EC2PDB4.4.1.16
ExplorEnz4.4.1.16
KEGG Ligand Database for Enzyme Nomenclature4.4.1.16
IUBMB Enzyme Nomenclature4.4.1.16
MEDLINEFind literature relating to 4.4.1.16
MetaCyc4.4.1.16
Rhea expert-curated reactions4.4.1.16
UniProtKB/Swiss-Prot
Q93WX6, CNIF1_ARATHQ46925, CSDA_ECOLIA2VDS1, SCLY_BOVIN
Q96I15, SCLY_HUMANQ9JLI6, SCLY_MOUSEQ68FT9, SCLY_RAT
Q66IQ6, SCLY_XENLAQ5U4Q9, SCLY_XENTRA8AH80, SUFS_CITK8
A7MF59, SUFS_CROS8Q9EXP2, SUFS_DICD3A7ZME5, SUFS_ECO24
B7US19, SUFS_ECO27B7MA32, SUFS_ECO45B7L5N2, SUFS_ECO55
Q7ADI4, SUFS_ECO57B5Z4B3, SUFS_ECO5EB7NTV6, SUFS_ECO7I
B7MV59, SUFS_ECO81B7M0N5, SUFS_ECO8AC4ZYE2, SUFS_ECOBW
B1XFY8, SUFS_ECODHA8A0M6, SUFS_ECOHSA1ABL8, SUFS_ECOK1
Q0THE9, SUFS_ECOL5Q8FH54, SUFS_ECOL6B1IQ76, SUFS_ECOLC
P77444, SUFS_ECOLIB7N516, SUFS_ECOLUB6IBB9, SUFS_ECOSE
B1LE56, SUFS_ECOSMQ1RBB6, SUFS_ECOUTA4W9R3, SUFS_ENT38
B7LQ96, SUFS_ESCF3D4GYV5, SUFS_HALVDA6TAE4, SUFS_KLEP7
B5XQH2, SUFS_KLEV3Q6D625, SUFS_PECASC6DKM6, SUFS_PECCP
Q7N3U5, SUFS_PHOLLB5F7C4, SUFS_SALA4A9MEP3, SUFS_SALAR
Q57PR2, SUFS_SALCHB5FIM3, SUFS_SALDCB5QVS9, SUFS_SALEP
B5RAT4, SUFS_SALG2B4TGK9, SUFS_SALHSB4T4R6, SUFS_SALNS
A9N142, SUFS_SALPBB4TUT5, SUFS_SALSVQ8XF77, SUFS_SALTI
Q7CQN5, SUFS_SALTYA8GDU4, SUFS_SERP5B2U2I4, SUFS_SHIB3
Q321D9, SUFS_SHIBSQ7UAH4, SUFS_SHIFLQ3Z233, SUFS_SHISS
Q8D2J7, SUFS_WIGBRA7FHJ2, SUFS_YERP3Q1C761, SUFS_YERPA
B2K5J4, SUFS_YERPBQ8D0M6, SUFS_YERPEA9QZC9, SUFS_YERPG
Q1CIJ6, SUFS_YERPNA4TIP2, SUFS_YERPPQ66A22, SUFS_YERPS
B1JJ48, SUFS_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-