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ENZYME entry: EC 4.4.1.20

Accepted Name
leukotriene-C4 synthase.
Alternative Name(s)
leukotriene A4:glutathione S-leukotrienyltransferase.
leukotriene C4 synthetase.
LTC4 synthase.
LTC4 synthetase.
Reaction catalysed
leukotriene C4 <=> glutathione + leukotriene A4
Comment(s)
  • The reaction proceeds in the direction of addition.
  • Not identical with EC 2.5.1.18.
  • Formerly EC 2.5.1.37.
Cross-references
BRENDA4.4.1.20
EC2PDB4.4.1.20
ExplorEnz4.4.1.20
PRIAM enzyme-specific profiles4.4.1.20
KEGG Ligand Database for Enzyme Nomenclature4.4.1.20
IUBMB Enzyme Nomenclature4.4.1.20
IntEnz4.4.1.20
MEDLINEFind literature relating to 4.4.1.20
MetaCyc4.4.1.20
Rhea expert-curated reactions4.4.1.20
UniProtKB/Swiss-Prot
Q03013, GSTM4_HUMAN;  Q8R5I6, GSTM4_MOUSE;  Q5BK56, GSTM4_RAT;  
Q2NKS0, LTC4S_BOVIN;  A6XA80, LTC4S_CAVPO;  Q16873, LTC4S_HUMAN;  
Q60860, LTC4S_MOUSE;  Q925U2, LTC4S_RAT;  Q2KJG4, MGST2_BOVIN;  
Q99735, MGST2_HUMAN;  A2RST1, MGST2_MOUSE;  O14880, MGST3_HUMAN;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.1.-
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