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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
S-alkylcysteine lyase.
Alternative Name(s)
S-alkyl-L-cysteine alkylthiol-lyase (deaminating).
S-alkyl-L-cysteine lyase.
S-alkyl-L-cysteine sulfoxide lyase.
Reaction catalysed
An S-alkyl-L-cysteine + H(2)O <=> an alkyl thiol + NH(3) + pyruvate
Pyridoxal 5'-phosphate.
  • Decomposes S-alkyl-L-cysteines by alpha,beta-elimination.
  • The enzyme cleaves a carbon-sulfur bond, releasing an alkyl thiol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.
  • The latter reaction, which can occur spontaneously, can also be catalyzed by EC
  • Possibly identical, in Saccharomyces cerevisiae, with EC
PRIAM enzyme-specific profiles4.4.1.6
KEGG Ligand Database for Enzyme Nomenclature4.4.1.6
IUBMB Enzyme Nomenclature4.4.1.6
MEDLINEFind literature relating to

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-