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ENZYME

ENZYME entry: EC 4.8.1.2

PURL: https://purl.expasy.org/enzyme/EC/4.8.1.2
Accepted Name
aliphatic aldoxime dehydratase
Alternative Name(s)
aliphatic aldoxime hydro-lyase
Reaction catalysed
an aliphatic aldoxime = a nitrile + H2O
Comment(s)
  • The enzyme from Pseudomonas chlororaphis contains Ca(2+) and protoheme IX, the iron of which must be in the form iron(II) for activity.
  • The enzyme exhibits a strong preference for aliphatic aldoximes, such as butyraldoxime and acetaldoxime, over aromatic aldoximes, such as pyridine-2-aldoxime, which is a poor substrate.
  • No activity was found with the aromatic aldoximes benzaldoxime and pyridine-4-aldoxime.
  • Formerly EC 4.99.1.5.
Cross-references
BRENDA4.8.1.2
EC2PDB4.8.1.2
ExplorEnz4.8.1.2
KEGG Ligand Database for Enzyme Nomenclature4.8.1.2
IUBMB Enzyme Nomenclature4.8.1.2
MEDLINEFind literature relating to 4.8.1.2
MetaCyc4.8.1.2
Rhea expert-curated reactions4.8.1.2
UniProtKB/Swiss-Prot
Q7WSJ4, OXD_PSECLQ4W7T3, OXD_PSESPQ76K71, OXD_RHOER
Q76EV4, OXD_RHOGO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-