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ENZYME entry: EC 4.99.1.11

Accepted Name
Sirohydrochlorin nickelchelatase.
Reaction catalysed
Ni-sirohydrochlorin + 2 H(+) <=> sirohydrochlorin + Ni(2+)
Comment(s)
  • The enzyme, studied from the methanogenic archaeon Methanosarcina acetivorans, participates in the biosynthesis of the nickel- containing tetrapyrrole cofactor coenzyme F(430), which is required by EC 2.8.4.1.
  • It catalyzes the insertion of the nickel ion into sirohydrochlorin.
Cross-references
BRENDA4.99.1.11
EC2PDB4.99.1.11
ExplorEnz4.99.1.11
PRIAM enzyme-specific profiles4.99.1.11
KEGG Ligand Database for Enzyme Nomenclature4.99.1.11
IUBMB Enzyme Nomenclature4.99.1.11
IntEnz4.99.1.11
MEDLINEFind literature relating to 4.99.1.11
MetaCyc4.99.1.11
Rhea expert-curated reactions4.99.1.11
UniProtKB/Swiss-Prot
A6UWT5, CFBA_META3;  Q8TJZ5, CFBA_METAC;  P61816, CFBA_METBF;  
Q12X56, CFBA_METBU;  Q58380, CFBA_METJA;  Q8TY77, CFBA_METKA;  
Q8PZH6, CFBA_METMA;  P61819, CFBA_METMP;  O27448, CFBA_METTH;  

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