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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 5.3.3.22

Accepted Name
Lutein isomerase.
Alternative Name(s)
Meso-zeaxanthin isomerase.
Reaction catalysed
Lutein <=> meso-zeaxanthin
Comment(s)
  • The enzyme is found in the retinal pigment epithelium (RPE) of vertebrates.
  • It also has the activity of EC 3.1.1.64.
Cross-references
BRENDA5.3.3.22
EC2PDB5.3.3.22
ExplorEnz5.3.3.22
PRIAM enzyme-specific profiles5.3.3.22
KEGG Ligand Database for Enzyme Nomenclature5.3.3.22
IUBMB Enzyme Nomenclature5.3.3.22
IntEnz5.3.3.22
MEDLINEFind literature relating to 5.3.3.22
MetaCyc5.3.3.22
UniProtKB/Swiss-Prot
Q6PBW5, RP65A_DANRE;  A9C3R9, RP65B_DANRE;  A9C3R8, RP65C_DANRE;  
Q9YI25, RPE65_AMBTI;  Q28175, RPE65_BOVIN;  Q9TVB8, RPE65_CANLF;  
Q9YGX2, RPE65_CHICK;  Q9XT71, RPE65_CHLAE;  Q8AXN9, RPE65_CYNPY;  
Q16518, RPE65_HUMAN;  Q91ZQ5, RPE65_MOUSE;  O70276, RPE65_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-