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ENZYME entry: EC 5.3.99.12
| Accepted Name |
|---|
| lachrymatory-factor synthase.
|
| Alternative Name(s) |
|---|
| LFS. |
| Reaction catalysed |
|---|
| (E)-alk-1-en-1-SO-peroxol <=> (Z)-alkanethial oxide |
| Comment(s) |
|---|
- The enzyme is responsible for production of the irritating
lachrymatory factor that is released by onions and related species
when they are chopped.
- It acts on the product of EC 4.4.1.4.
- The enzyme from Allium cepa (onion) acts on (E)-prop-1-en-1-
SO-peroxol and produces (Z)-propanethial oxide, while the enzyme from
Allium siculum (honey garlic) acts on (E)-but-1-en-1-SO-peroxol and
produces (Z)-butanethial oxide.
|
| Cross-references |
|---|
| BRENDA | 5.3.99.12 |
| EC2PDB | 5.3.99.12 |
| ExplorEnz | 5.3.99.12 |
| PRIAM enzyme-specific profiles | 5.3.99.12 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.3.99.12 |
| IUBMB Enzyme Nomenclature | 5.3.99.12 |
| IntEnz | 5.3.99.12 |
| MEDLINE | Find literature relating to 5.3.99.12 |
| MetaCyc | 5.3.99.12 |
| Rhea expert-curated reactions | 5.3.99.12 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 5.3.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-