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ENZYME entry: EC 5.4.99.17

Accepted Name
Squalene--hopene cyclase.
Reaction catalysed
Squalene <=> hop-22(29)-ene
Comment(s)
  • The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129).
  • Hopene and hopanol are formed at a constant ratio of 5:1.
Cross-references
PROSITEPDOC00825
BRENDA5.4.99.17
EC2PDB5.4.99.17
ExplorEnz5.4.99.17
PRIAM enzyme-specific profiles5.4.99.17
KEGG Ligand Database for Enzyme Nomenclature5.4.99.17
IUBMB Enzyme Nomenclature5.4.99.17
IntEnz5.4.99.17
MEDLINEFind literature relating to 5.4.99.17
MetaCyc5.4.99.17
Rhea expert-curated reactions5.4.99.17
UniProtKB/Swiss-Prot
P33247, SQHC_ALIAD;  P54924, SQHC_BRADU;  P55348, SQHC_SINFN;  
P33990, SQHC_ZYMMO;  

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