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ENZYME entry: EC 5.4.99.23

Accepted Name
23S rRNA pseudouridine(1911/1915/1917) synthase.
Reaction catalysed
23S rRNA uridine(1911)/uridine(1915)/uridine(1917) <=> 23S rRNA pseudouridine(1911)/pseudouridine(1915)/pseudouridine(1917)
Comment(s)
  • Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines.
  • These nucleotides are located in the functionally important helix- loop 69 of 23S rRNA.
Cross-references
BRENDA5.4.99.23
EC2PDB5.4.99.23
ExplorEnz5.4.99.23
PRIAM enzyme-specific profiles5.4.99.23
KEGG Ligand Database for Enzyme Nomenclature5.4.99.23
IUBMB Enzyme Nomenclature5.4.99.23
IntEnz5.4.99.23
MEDLINEFind literature relating to 5.4.99.23
MetaCyc5.4.99.23
Rhea expert-curated reactions5.4.99.23
UniProtKB/Swiss-Prot
P59838, RLUD_BLOFL;  P70870, RLUD_BORBU;  P57481, RLUD_BUCAI;  
Q8K9E9, RLUD_BUCAP;  Q89AD9, RLUD_BUCBP;  Q8X9F0, RLUD_ECO57;  
P65834, RLUD_ECOL6;  P33643, RLUD_ECOLI;  Q9L7A7, RLUD_HAEDU;  
P44445, RLUD_HAEIN;  Q9JVB6, RLUD_NEIMA;  Q9K0B0, RLUD_NEIMB;  
Q82WZ5, RLUD_NITEU;  Q9CKA6, RLUD_PASMU;  P33640, RLUD_PSEAE;  
Q8XYX8, RLUD_RALSO;  P65837, RLUD_SALTI;  P65836, RLUD_SALTY;  
P65835, RLUD_SHIFL;  Q9KU20, RLUD_VIBCH;  Q87S65, RLUD_VIBPA;  
Q8DEV0, RLUD_VIBVU;  Q8PHN2, RLUD_XANAC;  Q8P682, RLUD_XANCP;  
Q9PET9, RLUD_XYLFA;  Q87AR7, RLUD_XYLFT;  Q8ZBV7, RLUD_YERPE;  
P50513, RLUD_ZYMMO;  

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