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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 5.4.99.29

Accepted Name
23S rRNA pseudouridine(746) synthase.
Alternative Name(s)
23S RNA Psi(746) synthase.
Reaction catalysed
23S rRNA uridine(746) <=> 23S rRNA pseudouridine(746)
Comment(s)
  • RluA is the sole protein responsible for the in vivo formation of 23S RNA pseudouridine(746).
  • The dual-specificity enzyme also catalyzes the formation of uridine(32) in tRNA.
  • Cf. EC 5.4.99.28.
Cross-references
BRENDA5.4.99.29
EC2PDB5.4.99.29
ExplorEnz5.4.99.29
PRIAM enzyme-specific profiles5.4.99.29
KEGG Ligand Database for Enzyme Nomenclature5.4.99.29
IUBMB Enzyme Nomenclature5.4.99.29
IntEnz5.4.99.29
MEDLINEFind literature relating to 5.4.99.29
MetaCyc5.4.99.29
UniProtKB/Swiss-Prot
Q8XA10, RLUA_ECO57;  Q8FL93, RLUA_ECOL6;  P0AA37, RLUA_ECOLI;  
P59831, RLUA_HAEDU;  P44782, RLUA_HAEIN;  Q9CK02, RLUA_PASMU;  
Q8Z9J5, RLUA_SALTI;  Q8ZRV9, RLUA_SALTY;  P0AA38, RLUA_SHIFL;  
Q9KP71, RLUA_VIBCH;  Q87LD3, RLUA_VIBPA;  Q8DCG0, RLUA_VIBVU;  
Q8ZIK1, RLUA_YERPE;  

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