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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 5.4.99.41

Accepted Name
Lupeol synthase.
Reaction catalysed
(3S)-2,3-epoxy-2,3-dihydrosqualene <=> lupeol
Comment(s)
  • Also forms some beta-amyrin.
  • The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3-beta,20-diol with small amounts of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol.
  • See EC 4.2.1.128.
  • Formerly EC 5.4.99.n2.
Cross-references
BRENDA5.4.99.41
EC2PDB5.4.99.41
ExplorEnz5.4.99.41
PRIAM enzyme-specific profiles5.4.99.41
KEGG Ligand Database for Enzyme Nomenclature5.4.99.41
IUBMB Enzyme Nomenclature5.4.99.41
IntEnz5.4.99.41
MEDLINEFind literature relating to 5.4.99.41
MetaCyc5.4.99.41
UniProtKB/Swiss-Prot
Q9C5M3, LUP1_ARATH;  Q8RWT0, LUP2_ARATH;  Q8W3Z2, LUPS_BETPL;  
A8CDT3, LUPS_BRUGY;  Q764T8, LUPS_GLYGL;  E2IUA9, LUPS_KALDA;  
Q2XPU7, LUPS_RICCO;  

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