Expasy logo

ENZYME

ENZYME entry: EC 5.4.99.64

PURL: https://purl.expasy.org/enzyme/EC/5.4.99.64
Accepted Name
2-hydroxyisobutanoyl-CoA mutase
Reaction catalysed
2-hydroxyisobutanoyl-CoA = (3S)-3-hydroxybutanoyl-CoA
Comment(s)
  • The enzyme, characterized from the bacterium Aquincola tertiaricarbonis, uses radical chemistry to rearrange the positions of both a methyl group and a hydroxyl group.
  • It consists of two subunits, the smaller one containing a cobalamin cofactor.
  • It plays a central role in the degradation of assorted substrates containing a tert-butyl moiety.
  • Formerly EC 5.3.3.20.
Cross-references
Rhea expert-curated reactions5.4.99.64
ExplorEnz5.4.99.64
IUBMB Enzyme Nomenclature5.4.99.64
UniProtKB/Swiss-Prot
I3VE77, HCMA_AQUTEI3VE74, HCMB_AQUTE
BRENDA5.4.99.64
MetaCyc5.4.99.64
KEGG Ligand Database for Enzyme Nomenclature5.4.99.64
EC2PDB5.4.99.64
MEDLINEFind literature relating to 5.4.99.64

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-