ENZYME entry: EC 5.6.2.3
Accepted Name | |||||||||
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DNA 5'-3' helicase | |||||||||
Alternative Name(s) | |||||||||
5' to 3' DNA helicase | |||||||||
replication fork helicase | |||||||||
replicative DNA helicase | |||||||||
Reaction catalysed | |||||||||
Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction. This creates two antiparallel DNA single strands (ssDNA). The leading ssDNA polymer is the template for DNA polymerase III holoenzyme which synthesizes a continuous strand | |||||||||
Comment(s) | |||||||||
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Cross-references | |||||||||
BRENDA | 5.6.2.3 | ||||||||
EC2PDB | 5.6.2.3 | ||||||||
ExplorEnz | 5.6.2.3 | ||||||||
PRIAM enzyme-specific profiles | 5.6.2.3 | ||||||||
KEGG Ligand Database for Enzyme Nomenclature | 5.6.2.3 | ||||||||
IUBMB Enzyme Nomenclature | 5.6.2.3 | ||||||||
IntEnz | 5.6.2.3 | ||||||||
MEDLINE | Find literature relating to 5.6.2.3 | ||||||||
MetaCyc | 5.6.2.3 | ||||||||
Rhea expert-curated reactions | 5.6.2.3 | ||||||||
UniProtKB/Swiss-Prot |
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.6.2.-All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.6.-.-
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