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ENZYME

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ENZYME entry: EC 6.1.1.10

Accepted Name
methionine--tRNA ligase
Alternative Name(s)
methionine translase
methionyl-transfer ribonucleate synthetase
methionyl-transfer ribonucleic acid synthetase
methionyl-transfer RNA synthetase
methionyl-tRNA synthetase
MetRS
Reaction catalysed
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)
Comment(s)
In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
Cross-references
BRENDA6.1.1.10
EC2PDB6.1.1.10
ExplorEnz6.1.1.10
PRIAM enzyme-specific profiles6.1.1.10
KEGG Ligand Database for Enzyme Nomenclature6.1.1.10
IUBMB Enzyme Nomenclature6.1.1.10
IntEnz6.1.1.10
MEDLINEFind literature relating to 6.1.1.10
MetaCyc6.1.1.10
Rhea expert-curated reactions6.1.1.10
UniProtKB/Swiss-Prot
A8ZQ66, SYM1_ACAM1A8MG12, SYM1_ALKOOA0RKM3, SYM1_BACAH
Q81W03, SYM1_BACANQ72Y44, SYM1_BACC1Q81JA8, SYM1_BACCR
Q6HBM0, SYM1_BACHKA9FBU8, SYM1_SORC5Q81XF9, SYM2_BACAN
Q815U6, SYM2_BACCRQ9SVN5, SYMC_ARATHQ2T9L8, SYMC_BOVIN
Q20970, SYMC_CAEELQ54X95, SYMC_DICDIQ8SQW5, SYMC_ENCCU
P56192, SYMC_HUMANQ68FL6, SYMC_MOUSEQ9UUF2, SYMC_SCHPO
C4V943, SYMC_VAIC1Q6PF21, SYMC_XENLAP00958, SYMC_YEAST
Q9M2T9, SYMM_ARATHA6H7E1, SYMM_BOVINO74634, SYMM_CANAX
Q54MZ8, SYMM_DICDIQ9VFL5, SYMM_DROMEQ96GW9, SYMM_HUMAN
Q499X9, SYMM_MOUSEQ9C2H9, SYMM_NEUCRO14000, SYMM_SCHPO
Q90YI3, SYMM_TAKRUQ7T0Z0, SYMM_XENLAP22438, SYMM_YEAST
Q6FE36, SYM_ACIADB9MEX0, SYM_ACIETB7J7Y5, SYM_ACIF2
B5ENA8, SYM_ACIF5A1WBH1, SYM_ACISJA3MZ70, SYM_ACTP2
B3H0J7, SYM_ACTP7B0BTA2, SYM_ACTPJA6VQD5, SYM_ACTSZ
A0KKF6, SYM_AERHHQ9YCY3, SYM_AERPEQ8UFA2, SYM_AGRFC
Q21TB9, SYM_ALBFTQ0VP51, SYM_ALCBSQ5E3Z7, SYM_ALIF1
B5FG53, SYM_ALIFMB6EIY5, SYM_ALISLQ0AAG6, SYM_ALKEH
O67298, SYM_AQUAEO28819, SYM_ARCFUQ5P239, SYM_AROAE
A1KAG3, SYM_AZOSBC1DEF4, SYM_AZOVDC3P025, SYM_BACAA
C3LD96, SYM_BACACB7JEJ3, SYM_BACC0B7INU9, SYM_BACC2
C1EYD5, SYM_BACC3B7HD62, SYM_BACC4B7HVW2, SYM_BACC7
B9J4E0, SYM_BACCQQ5L7I8, SYM_BACFNQ64MP7, SYM_BACFR
A9VP41, SYM_BACMKP37465, SYM_BACSUQ8A3M1, SYM_BACTN
Q1LT75, SYM_BAUCHQ6MMA3, SYM_BDEBAC5C046, SYM_BEUC1
B8DT48, SYM_BIFA0A1A3N3, SYM_BIFAAP59076, SYM_BIFLO
B7GP85, SYM_BIFLSQ7VRX4, SYM_BLOFLQ492J8, SYM_BLOPB
Q2KYS4, SYM_BORA1Q0SMS1, SYM_BORAPQ7WP45, SYM_BORBR
Q44951, SYM_BORBUB7J2F0, SYM_BORBZB5RME0, SYM_BORDL
Q660T5, SYM_BORGPB2S0T6, SYM_BORHDQ7W1D8, SYM_BORPA
Q7W0F7, SYM_BORPEB5RPT6, SYM_BORRAA1R019, SYM_BORT9
Q8YH17, SYM_BRUMEP59078, SYM_BRUSUB8D8R1, SYM_BUCA5
P57210, SYM_BUCAIQ9ZHD7, SYM_BUCAPB8D715, SYM_BUCAT
Q89AX4, SYM_BUCBPB1YUT2, SYM_BURA4A0K9L0, SYM_BURCH
B4E8E0, SYM_BURCJQ0BCT3, SYM_BURCMQ39DV4, SYM_BURL3
A9AHJ8, SYM_BURM1A3MLM5, SYM_BURM7A2SAF7, SYM_BURM9
Q62LE0, SYM_BURMAA1V5W0, SYM_BURMSB1JWS3, SYM_BURO0
Q1BUH6, SYM_BURO1A3NSL6, SYM_BURP0Q3JUY1, SYM_BURP1
A3N6Y1, SYM_BURP6Q63W90, SYM_BURPSQ2T087, SYM_BURTA
A4JGW6, SYM_BURVGA8MA54, SYM_CALMQQ8RDD1, SYM_CALS4
Q9PP85, SYM_CAMJEB0T3J0, SYM_CAUSKQ9A884, SYM_CAUVC
B8H5U4, SYM_CAUVNA3PLG8, SYM_CERS1Q3J0T3, SYM_CERS4
A4WV24, SYM_CERS5B9KKH3, SYM_CERSKA9WKM1, SYM_CHLAA
Q5L5M3, SYM_CHLABB8G6F7, SYM_CHLADQ3AQR4, SYM_CHLCH
Q822N0, SYM_CHLCVQ255A6, SYM_CHLFFB3ECI3, SYM_CHLL2
Q3B3N3, SYM_CHLL3Q9PL07, SYM_CHLMUA1BF81, SYM_CHLPD
A4SE77, SYM_CHLPMQ9Z959, SYM_CHLPNB9LDY3, SYM_CHLSY
B0B9D9, SYM_CHLT2B3QT85, SYM_CHLT3Q3KMZ0, SYM_CHLTA
B0BB18, SYM_CHLTBP59077, SYM_CHLTEO84035, SYM_CHLTR
A0M5Z9, SYM_CHRFKQ1QVN7, SYM_CHRSDQ7NYR7, SYM_CHRVO
A8AEB2, SYM_CITK8Q97EW5, SYM_CLOABQ8XHG1, SYM_CLOPE
Q899D9, SYM_CLOTEQ480H5, SYM_COLP3Q6NIA5, SYM_CORDI
Q8FR00, SYM_COREFA4QCN5, SYM_CORGBQ8NRZ4, SYM_CORGL
Q4JU18, SYM_CORJKC4LHI6, SYM_CORK4B1VFI1, SYM_CORU7
B6J4V8, SYM_COXB1B6J3N7, SYM_COXB2A9KDF8, SYM_COXBN
A9NA60, SYM_COXBRQ83B24, SYM_COXBUA7MHL3, SYM_CROS8
Q1LJN4, SYM_CUPMCQ0K7K0, SYM_CUPNHQ474X7, SYM_CUPPJ
B3R678, SYM_CUPTRQ6A707, SYM_CUTAKQ11RM3, SYM_CYTH3
Q47IK0, SYM_DECARQ3Z9G6, SYM_DEHM1A5FS74, SYM_DEHMB
Q3ZZB2, SYM_DEHMCQ9RUF3, SYM_DEIRAA5EY62, SYM_DICNV
A8LIJ9, SYM_DINSHA7ZNT3, SYM_ECO24B7UFD1, SYM_ECO27
B7MEG9, SYM_ECO45B7L9Y6, SYM_ECO55Q8X7E7, SYM_ECO57
B5YV64, SYM_ECO5EB7NPL8, SYM_ECO7IB7MX36, SYM_ECO81
B7M4V9, SYM_ECO8AC4ZSJ8, SYM_ECOBWB1X7K4, SYM_ECODH
A8A1X8, SYM_ECOHSA1ACX8, SYM_ECOK1Q0TFX8, SYM_ECOL5
Q8FFX8, SYM_ECOL6B1IYW7, SYM_ECOLCP00959, SYM_ECOLI
B7NCE4, SYM_ECOLUB6HYV5, SYM_ECOSEB1LN54, SYM_ECOSM
Q1R9V8, SYM_ECOUTA4WCF6, SYM_ENT38Q837B3, SYM_ENTFA
B2VIF6, SYM_ERWT9B7LV75, SYM_ESCF3A5FLM7, SYM_FLAJ1
A6GVQ2, SYM_FLAPJQ14GV0, SYM_FRAT1A7NAE2, SYM_FRATF
Q2A4Y6, SYM_FRATHA0Q556, SYM_FRATNQ0BNA8, SYM_FRATO
Q5NFE7, SYM_FRATTA4IXI6, SYM_FRATWQ8RE57, SYM_FUSNN
P23920, SYM_GEOSEB8F3E3, SYM_GLAP5Q7VMC9, SYM_HAEDU
Q4QJZ5, SYM_HAEI8A5UBS8, SYM_HAEIEA5UF42, SYM_HAEIG
P43828, SYM_HAEINQ2SKU2, SYM_HAHCHQ9KGK8, SYM_HALH5
A1WUY7, SYM_HALHLQ5V1B3, SYM_HALMAB8D274, SYM_HALOH
Q9HSA4, SYM_HALSAQ18JV4, SYM_HALWDC4K759, SYM_HAMD5
Q9ZKG9, SYM_HELPJP56127, SYM_HELPYA4G3S6, SYM_HERAR
Q0I3W7, SYM_HISS1B0UV72, SYM_HISS2Q31GU1, SYM_HYDCU
A2BLU2, SYM_HYPBUQ0C161, SYM_HYPNAQ5R0G6, SYM_IDILO
A8ABN0, SYM_IGNH4A6SX05, SYM_JANMAQ28MK0, SYM_JANSC
A6W6U1, SYM_KINRDB5XP89, SYM_KLEP3A6TBK7, SYM_KLEP7
B1L7J9, SYM_KORCOQ9CHE0, SYM_LACLAQ88Z97, SYM_LACPL
Q5X105, SYM_LEGPAA5II55, SYM_LEGPCQ5ZRJ9, SYM_LEGPH
Q5WST1, SYM_LEGPLB0SHA8, SYM_LEPBAQ04Q66, SYM_LEPBJ
Q054R6, SYM_LEPBLB0SQX5, SYM_LEPBPB1XWM2, SYM_LEPCP
Q72MR4, SYM_LEPICQ8EZD6, SYM_LEPINQ92F90, SYM_LISIN
Q724N6, SYM_LISMFQ8YAF2, SYM_LISMOA0L8S1, SYM_MAGMM
Q65S22, SYM_MANSMQ0ANL8, SYM_MARMMA1TZ66, SYM_MARN8
A6UUN1, SYM_META3Q8TIU5, SYM_METACQ0W0H2, SYM_METAR
A7I6H7, SYM_METB6Q46F18, SYM_METBFQ12UQ9, SYM_METBU
Q60CR0, SYM_METCAQ1H2F4, SYM_METFKQ2FU77, SYM_METHJ
Q58659, SYM_METJAQ8TX28, SYM_METKAA2SRE2, SYM_METLZ
A4FZL1, SYM_METM5A6VIW5, SYM_METM7Q8PYJ4, SYM_METMA
A3CX39, SYM_METMJQ6M0E5, SYM_METMPB8GFL4, SYM_METPE
A2SEY3, SYM_METPPA5UJ98, SYM_METS3A4YI01, SYM_METS5
Q2NI31, SYM_METSTO26687, SYM_METTHA0B7K2, SYM_METTP
A6URW2, SYM_METVSQ5UR82, SYM_MIMIVP59952, SYM_MYCBO
P47267, SYM_MYCGEQ9CD55, SYM_MYCLEP75091, SYM_MYCPN
Q50319, SYM_MYCPUP9WFU4, SYM_MYCTOP9WFU5, SYM_MYCTU
Q1D8K2, SYM_MYXXDQ74MZ1, SYM_NANEQQ3IT47, SYM_NATPD
Q5F585, SYM_NEIG1A9LZS9, SYM_NEIM0Q9JWP0, SYM_NEIMA
Q9K1Q0, SYM_NEIMBA1KR57, SYM_NEIMFQ0AES9, SYM_NITEC
Q82WP0, SYM_NITEUQ2Y7P0, SYM_NITMUQ3JCG5, SYM_NITOC
A1SGG5, SYM_NOCSJQ8Z068, SYM_NOSS1P59079, SYM_OCEIH
Q9ZTS1, SYM_ORYSJA1TTU1, SYM_PARC0A6LFP0, SYM_PARD8
A1B3P3, SYM_PARDPQ6MDG0, SYM_PARUWQ143I7, SYM_PARXL
P57838, SYM_PASMUQ6D7B6, SYM_PECASC6DCI4, SYM_PECCP
B4SGQ6, SYM_PELPBQ7N6J6, SYM_PHOLLQ6LSZ7, SYM_PHOPR
A6KYR3, SYM_PHOV8Q6L1M5, SYM_PICTOA1VKF9, SYM_POLNA
Q12F12, SYM_POLSJB2RHF5, SYM_PORG3Q7MXK7, SYM_PORGI
B4ESY6, SYM_PROMHQ48LT7, SYM_PSE14Q15UM1, SYM_PSEA6
A6V1U3, SYM_PSEA7B7UWJ8, SYM_PSEA8Q02QX1, SYM_PSEAB
Q9HYC7, SYM_PSEAEQ1IDZ3, SYM_PSEE4Q4K758, SYM_PSEF5
C3KBZ7, SYM_PSEFSA4XS54, SYM_PSEMYA5VZI8, SYM_PSEP1
Q3K7L0, SYM_PSEPFB0KUD8, SYM_PSEPGQ88NV7, SYM_PSEPK
B1J1D1, SYM_PSEPWQ87XN0, SYM_PSESMQ3IL10, SYM_PSET1
Q4ZPK6, SYM_PSEU2Q4FRS8, SYM_PSYA2Q1QAD0, SYM_PSYCK
A1SVA5, SYM_PSYINA5WG58, SYM_PSYWFQ9V011, SYM_PYRAB
Q8ZU56, SYM_PYRAEA4WKG3, SYM_PYRARA3MVB7, SYM_PYRCJ
Q8U221, SYM_PYRFUO58721, SYM_PYRHOA1RRE2, SYM_PYRIL
B1YAZ7, SYM_PYRNVQ8XWT9, SYM_RALN1Q98MV8, SYM_RHILO
Q92PX0, SYM_RHIMEQ7URP3, SYM_RHOBAQ1RJZ5, SYM_RICBR
Q92GS6, SYM_RICCNQ4UMX2, SYM_RICFEQ9ZCP0, SYM_RICPR
Q68W54, SYM_RICTYA7NND5, SYM_ROSCSQ166L9, SYM_ROSDO
A5UUW9, SYM_ROSS1Q1AST1, SYM_RUBXDQ5LTL1, SYM_RUEPO
Q1GEI7, SYM_RUESTA1AWL4, SYM_RUTMCQ21I21, SYM_SACD2
A4F7W6, SYM_SACENQ9UWW2, SYM_SACS2B5EXZ5, SYM_SALA4
A8M218, SYM_SALAIA9MKV0, SYM_SALARQ57MI5, SYM_SALCH
B5FMX1, SYM_SALDCB5R0E7, SYM_SALEPB5RBZ5, SYM_SALG2
B4T9X0, SYM_SALHSB4SXY7, SYM_SALNSQ5PJ43, SYM_SALPA
A9N7I2, SYM_SALPBC0Q0Y1, SYM_SALPCB5BE81, SYM_SALPK
Q2S2A3, SYM_SALRDB4TNL2, SYM_SALSVQ8Z5C3, SYM_SALTI
A4X307, SYM_SALTOQ8ZNN4, SYM_SALTYA8GC37, SYM_SERP5
A1S798, SYM_SHEAMB8E958, SYM_SHEB2A3D5E5, SYM_SHEB5
A6WP56, SYM_SHEB8A9L4F6, SYM_SHEB9Q12MI8, SYM_SHEDO
Q081H3, SYM_SHEFNB0TJ05, SYM_SHEHHA3QD92, SYM_SHELP
Q8EDX2, SYM_SHEONA8H3V2, SYM_SHEPAA4Y7K8, SYM_SHEPC
A0KW24, SYM_SHESAA8FWN7, SYM_SHESHQ0HJN6, SYM_SHESM
Q0HVY2, SYM_SHESRA1RIY0, SYM_SHESWB1KQM2, SYM_SHEWM
B2TVX7, SYM_SHIB3Q323B4, SYM_SHIBSQ32EI8, SYM_SHIDS
Q0T324, SYM_SHIF8Q83KH0, SYM_SHIFLQ3Z096, SYM_SHISS
Q2NUD0, SYM_SODGMQ5HII6, SYM_STAACP67578, SYM_STAAM
P67579, SYM_STAANQ6GJI1, SYM_STAARQ6GBZ8, SYM_STAAS
Q8NY00, SYM_STAAWQ5HRR5, SYM_STAEQQ8CQU3, SYM_STAES
Q4L3E7, SYM_STAHJQ49UZ9, SYM_STAS1Q82F60, SYM_STRAW
Q9F2I9, SYM_STRCOB4SRG1, SYM_STRM5B2FPT0, SYM_STRMK
Q9A178, SYM_STRP1P0DG48, SYM_STRP3Q5XDK8, SYM_STRP6
C1C727, SYM_STRP7Q8P298, SYM_STRP8P67580, SYM_STRPN
P0DG49, SYM_STRPQB2IQ55, SYM_STRPSP67581, SYM_STRR6
A4VJ05, SYM_STUS1Q4J8M3, SYM_SULACC3MW97, SYM_SULIM
Q971C1, SYM_SULTOQ55729, SYM_SYNY3Q9HJ12, SYM_THEAC
Q47SZ0, SYM_THEFYQ5JDZ7, SYM_THEKOO33925, SYM_THEMA
B6YUN0, SYM_THEONA1RXT9, SYM_THEPDB9KZR0, SYM_THERP
P23395, SYM_THET8P59081, SYM_THEVBQ979B7, SYM_THEVO
Q3SKG8, SYM_THIDAC4LEX5, SYM_TOLATQ73NT9, SYM_TREDE
O83776, SYM_TREPAQ9PQU6, SYM_UREPAA1WRC4, SYM_VEREI
A5CWL9, SYM_VESOHB7VLW8, SYM_VIBA3A7MZT3, SYM_VIBC1
A5F2P8, SYM_VIBC3Q9KT69, SYM_VIBCHQ87N07, SYM_VIBPA
Q8D8F2, SYM_VIBVUQ7MM14, SYM_VIBVYQ8D219, SYM_WIGBR
Q8PMP0, SYM_XANACQ4USM5, SYM_XANC8B0RWA1, SYM_XANCB
Q8PAY7, SYM_XANCPQ3BVP1, SYM_XANE5Q2P4E9, SYM_XANOM
B2SRQ4, SYM_XANOPQ5H1J3, SYM_XANORB2I7S0, SYM_XYLF2
Q9PFV8, SYM_XYLFAB0U472, SYM_XYLFMQ87B68, SYM_XYLFT
A1JTX6, SYM_YERE8A7FJJ6, SYM_YERP3Q1C9T8, SYM_YERPA
B2JZK3, SYM_YERPBQ8ZG01, SYM_YERPEA9R2M7, SYM_YERPG
Q1CGU4, SYM_YERPNA4TKM9, SYM_YERPPQ66C72, SYM_YERPS
B1JPY8, SYM_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-