ENZYME entry: EC 6.1.1.13

Accepted Name
D-alanine--poly(phosphoribitol) ligase.
Alternative Name(s)
D-alanine-activating enzyme.
D-alanine-D-alanyl carrier protein ligase.
D-alanine-membrane acceptor ligase.
D-alanine: membrane acceptor ligase.
D-alanyl-poly(phosphoribitol) synthetase.
Reaction catalysed
ATP + D-alanine + poly(ribitol phosphate) <=> AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
Comment(s)
  • A thioester bond is formed transiently between D-alanine and the sulfhydryl group of the 4'-phosphopantetheine prosthetic group of D-alanyl carrier protein during the activation of the alanine.
  • Involved in the synthesis of teichoic acids.
Cross-references
BRENDA6.1.1.13
EC2PDB6.1.1.13
ExplorEnz6.1.1.13
PRIAM enzyme-specific profiles6.1.1.13
KEGG Ligand Database for Enzyme Nomenclature6.1.1.13
IUBMB Enzyme Nomenclature6.1.1.13
IntEnz6.1.1.13
MEDLINEFind literature relating to 6.1.1.13
MetaCyc6.1.1.13

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