A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 6.1.2.2
| Accepted Name |
|---|
| Nebramycin 5' synthase.
|
| Alternative Name(s) |
|---|
| Tobramycin carbamoyltransferase. |
| Reaction catalysed |
|---|
- Tobramycin + carbamoyl phosphate + ATP + H(2)O <=> nebramycin 5' + AMP + diphosphate + phosphate
- Kanamycin A + carbamoyl phosphate + ATP + H(2)O <=> 6''-O-carbamoylkanamycin A + AMP + diphosphate + phosphate
|
| Cofactor(s) |
|---|
| Fe(3+).
|
| Comment(s) |
|---|
- The enzyme from the bacterium Streptoalloteichus tenebrarius
catalyzes the activation of carbamoyl phosphate to
O-carbamoyladenylate and the subsequent carbamoylation of kanamycin
and tobramycin.
- Formerly EC 2.1.3.13 and EC 2.1.3.14.
|
| Cross-references |
|---|
| BRENDA | 6.1.2.2 |
| EC2PDB | 6.1.2.2 |
| ExplorEnz | 6.1.2.2 |
| PRIAM enzyme-specific profiles | 6.1.2.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.1.2.2 |
| IUBMB Enzyme Nomenclature | 6.1.2.2 |
| IntEnz | 6.1.2.2 |
| MEDLINE | Find literature relating to 6.1.2.2 |
| MetaCyc | 6.1.2.2 |
| UniProtKB/Swiss-Prot |
|
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UniProtKB/Swiss-Prot entries corresponding to 6.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-