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ENZYME

ENZYME entry: EC 6.2.1.49

PURL: https://purl.expasy.org/enzyme/EC/6.2.1.49
Accepted Name
long-chain fatty acid adenylyltransferase FadD28
Reaction catalysed
holo-[mycocerosate synthase] + a long-chain fatty acid + ATP = a long-chain fatty acyl-[mycocerosate synthase] + AMP + diphosphate
Comment(s)
  • The enzyme, found in certain mycobacteria, activates long-chain fatty acids by adenylation and transfers them to EC 2.3.1.111.
  • The enzyme participates in the biosynthesis of the virulent lipids dimycocerosates (DIM) and dimycocerosyl triglycosyl phenolphthiocerol (PGL).
  • Formerly EC 2.7.7.95.
Cross-references
Rhea expert-curated reactions6.2.1.49
ExplorEnz6.2.1.49
IUBMB Enzyme Nomenclature6.2.1.49
UniProtKB/Swiss-Prot
Q02278, FAA28_MYCBOB2HIM0, FAA28_MYCMMP9WQ58, FAA28_MYCTO
P9WQ59, FAA28_MYCTU
BRENDA6.2.1.49
MetaCyc6.2.1.49
KEGG Ligand Database for Enzyme Nomenclature6.2.1.49
EC2PDB6.2.1.49
MEDLINEFind literature relating to 6.2.1.49

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-