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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 6.2.1.49

Accepted Name
Long-chain fatty acid adenylyltransferase FadD28.
Reaction catalysed
ATP + a long-chain fatty acid + holo-[mycocerosate synthase] <=> AMP + diphosphate + a long-chain acyl-[mycocerosate synthase]
Comment(s)
  • The enzyme, found in certain mycobacteria, activates long-chain fatty acids by adenylation and transfers them to EC 2.3.1.111.
  • The enzyme participates in the biosynthesis of the virulent lipids dimycocerosates (DIM) and dimycocerosyl triglycosyl phenolphthiocerol (PGL).
  • Formerly EC 2.7.7.95.
Cross-references
BRENDA6.2.1.49
EC2PDB6.2.1.49
ExplorEnz6.2.1.49
PRIAM enzyme-specific profiles6.2.1.49
KEGG Ligand Database for Enzyme Nomenclature6.2.1.49
IUBMB Enzyme Nomenclature6.2.1.49
IntEnz6.2.1.49
MEDLINEFind literature relating to 6.2.1.49
MetaCyc6.2.1.49

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-