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ENZYME entry: EC 6.3.1.15

Accepted Name
8-demethylnovobiocic acid synthase.
Alternative Name(s)
8-demethylnovobiocic acid synthetase.
Novobiocin ligase.
Reaction catalysed
ATP + 3-dimethylallyl-4-hydroxybenzoate + 3-amino-4,7-dihydroxycoumarin <=> AMP + diphosphate + 8-demethylnovobiocic acid
Comment(s)
The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin.
Cross-references
BRENDA6.3.1.15
EC2PDB6.3.1.15
ExplorEnz6.3.1.15
PRIAM enzyme-specific profiles6.3.1.15
KEGG Ligand Database for Enzyme Nomenclature6.3.1.15
IUBMB Enzyme Nomenclature6.3.1.15
IntEnz6.3.1.15
MEDLINEFind literature relating to 6.3.1.15
MetaCyc6.3.1.15
Rhea expert-curated reactions6.3.1.15
UniProtKB/Swiss-Prot
Q9L9F6, NOVL_STRNV

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