ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME class: 6.3

Release of 16-Jan-19

Ligases
Forming carbon-nitrogen bonds

The following ENZYME entries belong to class 6.3.-.-:

6.3.1.1      Aspartate--ammonia ligase
6.3.1.2      Glutamine synthetase
6.3.1.3      Transferred entry: 6.3.4.13
6.3.1.4      Aspartate--ammonia ligase (ADP-forming)
6.3.1.5      NAD(+) synthase
6.3.1.6      Glutamate--ethylamine ligase
6.3.1.7      4-methyleneglutamate--ammonia ligase
6.3.1.8      Glutathionylspermidine synthase
6.3.1.9      Trypanothione synthase
6.3.1.10     Adenosylcobinamide-phosphate synthase
6.3.1.11     Glutamate--putrescine ligase
6.3.1.12     D-aspartate ligase
6.3.1.13     L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside
             ligase
6.3.1.14     Diphthine--ammonia ligase
6.3.1.15     8-demethylnovobiocic acid synthase
6.3.1.16     Transferred entry: 6.3.3.6
6.3.1.17     Beta-citrylglutamate synthase
6.3.1.18     Gamma-glutamylanilide synthase
6.3.1.19     Prokaryotic ubiquitin-like protein ligase
6.3.1.20     Lipoate--protein ligase
6.3.2.1      Pantoate--beta-alanine ligase (AMP-forming)
6.3.2.2      Glutamate--cysteine ligase
6.3.2.3      Glutathione synthase
6.3.2.4      D-alanine--D-alanine ligase
6.3.2.5      Phosphopantothenate--cysteine ligase (CTP)
6.3.2.6      Phosphoribosylaminoimidazolesuccinocarboxamide synthase
6.3.2.7      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase
6.3.2.8      UDP-N-acetylmuramate--L-alanine ligase
6.3.2.9      UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
6.3.2.10     UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
6.3.2.11     Carnosine synthase
6.3.2.12     Dihydrofolate synthase
6.3.2.13     UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
6.3.2.14     Enterobactin synthase
6.3.2.15     Transferred entry: 6.3.2.10
6.3.2.16     D-alanine--alanyl-poly(glycerolphosphate) ligase
6.3.2.17     Tetrahydrofolate synthase
6.3.2.18     Gamma-glutamylhistamine synthase
6.3.2.19     Transferred entry: 2.3.2.23, 2.3.2.27 and 6.2.1.45
6.3.2.20     Indoleacetate--lysine synthetase
6.3.2.21     Transferred entry: 2.3.2.27 and 6.2.1.45
6.3.2.22     Transferred entry: 6.3.1.14
6.3.2.23     Homoglutathione synthase
6.3.2.24     Tyrosine--arginine ligase
6.3.2.25     Tubulin--tyrosine ligase
6.3.2.26     N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
6.3.2.27     Transferred entry: 6.3.2.38 and 6.3.2.39
6.3.2.28     Transferred entry: 6.3.2.49
6.3.2.29     Cyanophycin synthase (L-aspartate-adding)
6.3.2.30     Cyanophycin synthase (L-arginine-adding)
6.3.2.31     Coenzyme F420-0:L-glutamate ligase
6.3.2.32     Coenzyme gamma-F420-2:alpha-L-glutamate ligase
6.3.2.33     Tetrahydrosarcinapterin synthase
6.3.2.34     Coenzyme F420-1:gamma-L-glutamate ligase
6.3.2.35     D-alanine--D-serine ligase
6.3.2.36     4-phosphopantoate--beta-alanine ligase
6.3.2.37     UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase
6.3.2.38     N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase
6.3.2.39     Aerobactin synthase
6.3.2.40     Cyclopeptine synthase
6.3.2.41     N-acetylaspartylglutamate synthase
6.3.2.42     N-acetylaspartylglutamylglutamate synthase
6.3.2.43     [Lysine-biosynthesis-protein LysW]--L-2-aminoadipate ligase
6.3.2.44     Pantoate--beta-alanine ligase (ADP-forming)
6.3.2.45     UDP-N-acetylmuramate L-alanyl-gamma-D-glutamyl-meso-2,6-
             diaminoheptanedioate ligase
6.3.2.46     Fumarate--(S)-2,3-diaminopropanoate ligase
6.3.2.47     Dapdiamide synthase
6.3.2.48     L-arginine-specific L-amino acid ligase
6.3.2.49     L-alanine--L-anticapsin ligase
6.3.2.50     Tenuazonic acid synthetase
6.3.2.51     Phosphopantothenate--cysteine ligase (ATP)
6.3.2.52     Jasmonoyl--L-amino acid synthetase
6.3.2.n1     Transferred entry: 6.3.2.37
6.3.2.n2     Transferred entry: 6.3.1.19
6.3.2.n3     ISG15--protein ligase
6.3.2.n4     Transferred entry: 6.3.2.43
6.3.2.n5     Transferred entry: 6.3.2.44
6.3.2.n6     Transferred entry: 6.3.2.41
6.3.3.1      Phosphoribosylformylglycinamidine cyclo-ligase
6.3.3.2      5-formyltetrahydrofolate cyclo-ligase
6.3.3.3      Dethiobiotin synthase
6.3.3.4      (Carboxyethyl)arginine beta-lactam-synthase
6.3.3.5      O-ureido-D-serine cyclo-ligase
6.3.3.6      Carbapenam-3-carboxylate synthase
6.3.3.7      Ni-sirohydrochlorin a,c-diamide reductive cyclase
6.3.4.1      Transferred entry: 6.3.5.2
6.3.4.2      CTP synthase (glutamine hydrolyzing)
6.3.4.3      Formate--tetrahydrofolate ligase
6.3.4.4      Adenylosuccinate synthase
6.3.4.5      Argininosuccinate synthase
6.3.4.6      Urea carboxylase
6.3.4.7      Ribose-5-phosphate--ammonia ligase
6.3.4.8      Imidazoleacetate--phosphoribosyldiphosphate ligase
6.3.4.9      Biotin--[methylmalonyl-CoA-carboxytransferase] ligase
6.3.4.10     Biotin--[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase
6.3.4.11     Biotin--[methylcrotonoyl-CoA-carboxylase] ligase
6.3.4.12     Glutamate--methylamine ligase
6.3.4.13     Phosphoribosylamine--glycine ligase
6.3.4.14     Biotin carboxylase
6.3.4.15     Biotin--[biotin carboxyl-carrier protein] ligase
6.3.4.16     Carbamoyl-phosphate synthase (ammonia)
6.3.4.17     Formate--dihydrofolate ligase
6.3.4.18     5-(carboxyamino)imidazole ribonucleotide synthase
6.3.4.19     tRNA(Ile)-lysidine synthetase
6.3.4.20     7-cyano-7-deazaguanine synthase
6.3.4.21     Nicotinate phosphoribosyltransferase
6.3.4.22     tRNA(Ile)(2)-agmatinylcytidine synthase
6.3.4.23     Formate--phosphoribosylaminoimidazolecarboxamide ligase
6.3.4.24     Tyramine--L-glutamate ligase
6.3.5.1      NAD(+) synthase (glutamine-hydrolyzing)
6.3.5.2      GMP synthase (glutamine-hydrolyzing)
6.3.5.3      Phosphoribosylformylglycinamidine synthase
6.3.5.4      Asparagine synthase (glutamine-hydrolyzing)
6.3.5.5      Carbamoyl-phosphate synthase (glutamine-hydrolyzing)
6.3.5.6      Asparaginyl-tRNA synthase (glutamine-hydrolyzing)
6.3.5.7      Glutaminyl-tRNA synthase (glutamine-hydrolyzing)
6.3.5.8      Transferred entry: 2.6.1.85
6.3.5.9      Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing)
6.3.5.10     Adenosylcobyric acid synthase (glutamine-hydrolyzing)
6.3.5.11     Cobyrinate a,c-diamide synthase (glutamine-hydrolyzing)
6.3.5.12     Ni-sirohydrochlorin a,c-diamide synthase