Due to maintenance work, this service will be unavailable Mon Feb 13 between
07:00 and
09:30 -
CET.
Apologies for the inconvenience.
ENZYME entry: EC 6.3.1.8
Accepted Name |
glutathionylspermidine synthase.
|
Alternative Name(s) |
gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming). |
glutathione:spermidine ligase (ADP-forming). |
glutathionylspermidine synthetase. |
GSP synthetase. |
Reaction catalysed |
ATP + glutathione + spermidine <=> ADP + glutathionylspermidine + H(+) + phosphate |
Comment(s) |
- Involved in the synthesis of trypanothione in trypanosomatids.
- The enzyme from Escherichia coli is bifunctional and also catalyzes
the EC 3.5.1.78 reaction, resulting in a net hydrolysis of ATP.
|
Cross-references |
BRENDA | 6.3.1.8 |
EC2PDB | 6.3.1.8 |
ExplorEnz | 6.3.1.8 |
PRIAM enzyme-specific profiles | 6.3.1.8 |
KEGG Ligand Database for Enzyme Nomenclature | 6.3.1.8 |
IUBMB Enzyme Nomenclature | 6.3.1.8 |
IntEnz | 6.3.1.8 |
MEDLINE | Find literature relating to 6.3.1.8 |
MetaCyc | 6.3.1.8 |
Rhea expert-curated reactions | 6.3.1.8 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-