ENZYME entry: EC 6.3.2.11
Accepted Name |
carnosine synthase.
|
Alternative Name(s) |
carnosine synthetase. |
Reaction catalysed |
ATP + beta-alanine + L-histidine <=> ADP + carnosine + H(+) + phosphate |
Comment(s) |
- This enzyme was thought to form AMP, but studies with highly purified
enzyme proved that it forms ADP.
- Carnosine is a dipeptide that is present at high concentrations in
skeletal muscle and the olfactory bulb of vertebrates.
- It is also found in the skeletal muscle of some invertebrates.
- The enzyme can also catalyze the formation of homocarnosine from
4-aminobutyrate and L-histidine, with much lower activity.
|
Cross-references |
BRENDA | 6.3.2.11 |
EC2PDB | 6.3.2.11 |
ExplorEnz | 6.3.2.11 |
PRIAM enzyme-specific profiles | 6.3.2.11 |
KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.11 |
IUBMB Enzyme Nomenclature | 6.3.2.11 |
IntEnz | 6.3.2.11 |
MEDLINE | Find literature relating to 6.3.2.11 |
MetaCyc | 6.3.2.11 |
Rhea expert-curated reactions | 6.3.2.11 |
UniProtKB/Swiss-Prot |
|
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