ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 6.3.2.30

Accepted Name

Cyanophycin synthase (L-arginine-adding).

Alternative Name(s)

Cyanophycin synthetase.

Multi-L-arginyl-poly-L-aspartate synthase.

Reaction catalysed

ATP + (L-Asp(4-L-Arg))(n)-L-Asp + L-Arg <=> ADP + phosphate + (L-Asp(4-L-Arg))(n+1)

Cofactor(s)

Mg(2+).

Comment(s)

Both this enzyme and EC 6.3.2.29 are required for the elongation of cyanophycin, which is a protein-like cell inclusion that is unique to cyanobacteria and acts as a temporary nitrogen store.
Both enzymes are found in the same protein but have different active sites.
Both L-Asp and L-Arg must be present before either enzyme will display significant activity.
Canavanine and lysine can be incoporated into the polymer instead of arginine.

Cross-references

PROSITE

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature