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ENZYME entry: EC 6.3.2.40

Accepted Name
cyclopeptine synthase.
Reaction catalysed
anthranilate + 2 ATP + L-phenylalanine + S-adenosyl-L-methionine <=> 2 AMP + cyclopeptine + 2 diphosphate + 2 H(+) + S-adenosyl-L-homocysteine
Comment(s)
  • Cyclopeptine synthase is the key enzyme of benzodiazepine alkaloid biosynthesis in the fungus Penicillium cyclopium.
  • The enzyme is a non-ribosomal peptide synthase.
  • Formerly EC 2.7.7.54 and EC 2.7.7.55.
Cross-references
BRENDA6.3.2.40
EC2PDB6.3.2.40
ExplorEnz6.3.2.40
PRIAM enzyme-specific profiles6.3.2.40
KEGG Ligand Database for Enzyme Nomenclature6.3.2.40
IUBMB Enzyme Nomenclature6.3.2.40
IntEnz6.3.2.40
MEDLINEFind literature relating to 6.3.2.40
MetaCyc6.3.2.40
Rhea expert-curated reactions6.3.2.40

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-