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ENZYME entry: EC 6.3.2.44

Accepted Name
pantoate--beta-alanine ligase (ADP-forming).
Alternative Name(s)
pantoate--beta-alanine ligase.
pantothenate synthetase.
Reaction catalysed
(R)-pantoate + ATP + beta-alanine <=> (R)-pantothenate + ADP + H(+) + phosphate
Comment(s)
  • The enzyme, characterized from the archaeon Methanosarcina mazei, is involved in the biosynthesis of pantothenate.
  • It is different from EC 6.3.2.1, the AMP-forming pantoate-beta- alanine ligase found in bacteria and eukaryota.
  • Formerly EC 6.3.2.n5.
Cross-references
BRENDA6.3.2.44
EC2PDB6.3.2.44
ExplorEnz6.3.2.44
PRIAM enzyme-specific profiles6.3.2.44
KEGG Ligand Database for Enzyme Nomenclature6.3.2.44
IUBMB Enzyme Nomenclature6.3.2.44
IntEnz6.3.2.44
MEDLINEFind literature relating to 6.3.2.44
MetaCyc6.3.2.44
Rhea expert-curated reactions6.3.2.44

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-