ENZYME entry: EC 6.3.2.58
| Accepted Name |
|---|
| D-ornithine--citrate ligase.
|
| Reaction catalysed |
|---|
| ATP + D-ornithine + citrate <=> AMP + diphosphate + N(5)-((S)-citryl)-D-ornithine |
| Comment(s) |
|---|
- Requires Mg(2+).
- The enzyme, characterized from the bacterium Staphylococcus aureus,
is involved in the biosynthesis of the siderophore staphyloferrin A.
- It belongs to a class of siderophore synthases known as type A
nonribosomal peptide synthase-independent synthases (NIS).
- Type A NIS enzymes are responsible for the formation of amide or
ester bonds between polyamines or amino alcohols and a prochiral
carboxyl group of citrate.
- The enzyme forms a citrate adenylate intermediate prior to ligation.
|
| Cross-references |
|---|
| BRENDA | 6.3.2.58 |
| EC2PDB | 6.3.2.58 |
| ExplorEnz | 6.3.2.58 |
| PRIAM enzyme-specific profiles | 6.3.2.58 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.58 |
| IUBMB Enzyme Nomenclature | 6.3.2.58 |
| IntEnz | 6.3.2.58 |
| MEDLINE | Find literature relating to 6.3.2.58 |
| MetaCyc | 6.3.2.58 |
| Rhea expert-curated reactions | 6.3.2.58 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-