Due to maintenance work, this service will be unavailable Mon Feb 13 between
07:00 and
09:30 -
CET.
Apologies for the inconvenience.
ENZYME entry: EC 6.3.2.58
Accepted Name |
D-ornithine--citrate ligase.
|
Reaction catalysed |
ATP + citrate + D-ornithine <=> AMP + diphosphate + H(+) + N(5)-[(S)-citryl]-D-ornithine |
Comment(s) |
- Requires Mg(2+).
- The enzyme, characterized from the bacterium Staphylococcus aureus,
is involved in the biosynthesis of the siderophore staphyloferrin A.
- It belongs to a class of siderophore synthases known as type A
nonribosomal peptide synthase-independent synthases (NIS).
- Type A NIS enzymes are responsible for the formation of amide or
ester bonds between polyamines or amino alcohols and a prochiral
carboxyl group of citrate.
- The enzyme forms a citrate adenylate intermediate prior to ligation.
|
Cross-references |
BRENDA | 6.3.2.58 |
EC2PDB | 6.3.2.58 |
ExplorEnz | 6.3.2.58 |
PRIAM enzyme-specific profiles | 6.3.2.58 |
KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.58 |
IUBMB Enzyme Nomenclature | 6.3.2.58 |
IntEnz | 6.3.2.58 |
MEDLINE | Find literature relating to 6.3.2.58 |
MetaCyc | 6.3.2.58 |
Rhea expert-curated reactions | 6.3.2.58 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-