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ENZYME

ENZYME entry: EC 6.3.2.59

PURL: https://purl.expasy.org/enzyme/EC/6.3.2.59
Accepted Name
3-methyl-D-ornithine--L-lysine ligase
Alternative Name(s)
3-methylornithine--L-lysine ligase
N(6)-[(2R,3R)-3-methylornithyl]-L-lysine synthase
Reaction catalysed
(3R)-3-methyl-D-ornithine + L-lysine + ATP = (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + ADP + phosphate + H(+)
Comment(s)
  • The enzyme participates in the biosynthesis of L-pyrrolysine, a naturally occurring, genetically coded amino acid found in some methanogenic archaea and a few bacterial species.
  • L-pyrrolysine is present in several methyltransferases that are involved in methyl transfer from methylated amine compounds to coenzyme M.
Cross-references
BRENDA6.3.2.59
EC2PDB6.3.2.59
ExplorEnz6.3.2.59
KEGG Ligand Database for Enzyme Nomenclature6.3.2.59
IUBMB Enzyme Nomenclature6.3.2.59
MEDLINEFind literature relating to 6.3.2.59
MetaCyc6.3.2.59
Rhea expert-curated reactions6.3.2.59
UniProtKB/Swiss-Prot
Q8TUC0, PYLC_METACQ46E79, PYLC_METBFQ8PWY3, PYLC_METMA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-