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ENZYME entry: EC 6.3.3.6

Accepted Name
carbapenam-3-carboxylate synthase.
Alternative Name(s)
carbapenam-3-carboxylate ligase.
Reaction catalysed
(2S,5S)-5-carboxymethylproline + ATP <=> (3S,5S)-carbapenam-3-caboxylate + AMP + diphosphate + H(+)
Comment(s)
  • The enzyme is involved in the biosynthesis of the carbapenem beta- lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum.
  • Formerly EC 6.3.1.16.
Cross-references
BRENDA6.3.3.6
EC2PDB6.3.3.6
ExplorEnz6.3.3.6
PRIAM enzyme-specific profiles6.3.3.6
KEGG Ligand Database for Enzyme Nomenclature6.3.3.6
IUBMB Enzyme Nomenclature6.3.3.6
IntEnz6.3.3.6
MEDLINEFind literature relating to 6.3.3.6
MetaCyc6.3.3.6
Rhea expert-curated reactions6.3.3.6
UniProtKB/Swiss-Prot
Q9XB61, CARA_PECCC

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