ENZYME entry: EC 6.3.5.10
| Accepted Name |
|---|
| Adenosylcobyric acid synthase (glutamine-hydrolyzing).
|
| Alternative Name(s) |
|---|
| 5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase. |
| Ado-cobyric acid synthase (glutamine hydrolyzing). |
| Cobyric acid synthase. |
| Reaction catalysed |
|---|
| 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H(2)O <=> 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate |
| Cofactor(s) |
|---|
| Mg(2+).
|
| Comment(s) |
|---|
- NH(3) can act instead of glutamine.
- This enzyme catalyzes the four-step amidation sequence from cobyrinic
acid a,c-diamide to cobyric acid via the formation of cobyrinic acid
triamide, tetraamide and pentaamide intermediates.
|
| Cross-references |
|---|
| BRENDA | 6.3.5.10 |
| EC2PDB | 6.3.5.10 |
| ExplorEnz | 6.3.5.10 |
| PRIAM enzyme-specific profiles | 6.3.5.10 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.5.10 |
| IUBMB Enzyme Nomenclature | 6.3.5.10 |
| IntEnz | 6.3.5.10 |
| MEDLINE | Find literature relating to 6.3.5.10 |
| MetaCyc | 6.3.5.10 |
| Rhea expert-curated reactions | 6.3.5.10 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-