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ENZYME

ENZYME entry: EC 6.3.5.3

PURL: https://purl.expasy.org/enzyme/EC/6.3.5.3
Accepted Name
phosphoribosylformylglycinamidine synthase
Alternative Name(s)
FGAM synthase
FGAM synthetase
FGAR amidotransferase
FGARAT
formylglycinamide ribotide amidotransferase
phosphoribosylformylglycinamidine synthetase
Reaction catalysed
N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)
Cross-references
BRENDA6.3.5.3
EC2PDB6.3.5.3
ExplorEnz6.3.5.3
KEGG Ligand Database for Enzyme Nomenclature6.3.5.3
IUBMB Enzyme Nomenclature6.3.5.3
MEDLINEFind literature relating to 6.3.5.3
MetaCyc6.3.5.3
Rhea expert-curated reactions6.3.5.3
UniProtKB/Swiss-Prot
Q5E749, PUR4_ALIF1Q9M8D3, PUR4_ARATHQ19311, PUR4_CAEEL
Q47XX7, PUR4_COLP3Q54JC8, PUR4_DICDIP35421, PUR4_DROME
Q8XA46, PUR4_ECO57Q0TET1, PUR4_ECOL5Q8FF26, PUR4_ECOL6
P15254, PUR4_ECOLIQ1R8H7, PUR4_ECOUTQ4QME6, PUR4_HAEI8
P43847, PUR4_HAEINQ2SK05, PUR4_HAHCHQ0I5H4, PUR4_HISS1
O15067, PUR4_HUMANQ5QWY0, PUR4_IDILOQ65RJ7, PUR4_MANSM
Q1H2I8, PUR4_METFKQ5SUR0, PUR4_MOUSEQ1D9V4, PUR4_MYXXD
Q5F7J4, PUR4_NEIG1Q9JWC5, PUR4_NEIMAQ9JXK5, PUR4_NEIMB
Q9CLW4, PUR4_PASMUQ6D238, PUR4_PECASQ7N1Z4, PUR4_PHOLL
Q6LU24, PUR4_PHOPRQ48LX3, PUR4_PSE14Q15R69, PUR4_PSEA6
Q9HXN2, PUR4_PSEAEQ4KHS6, PUR4_PSEF5Q3KHL4, PUR4_PSEPF
Q88P16, PUR4_PSEPKQ886W6, PUR4_PSESMQ3IHZ2, PUR4_PSET1
Q4ZX02, PUR4_PSEU2Q8XYN6, PUR4_RALN1Q57LE6, PUR4_SALCH
Q5PIG8, PUR4_SALPAQ8Z4L6, PUR4_SALTIP74881, PUR4_SALTY
O14228, PUR4_SCHPOQ12PR7, PUR4_SHEDOQ085S1, PUR4_SHEFN
Q8EC57, PUR4_SHEONQ0HKU9, PUR4_SHESMQ0HX47, PUR4_SHESR
Q31XT0, PUR4_SHIBSQ32D15, PUR4_SHIDSQ3YYZ8, PUR4_SHISS
Q2NS22, PUR4_SODGMQ9KTN2, PUR4_VIBCHQ87RW0, PUR4_VIBPA
Q8DF81, PUR4_VIBVUQ7MN70, PUR4_VIBVYQ8PGR7, PUR4_XANAC
Q8PCQ7, PUR4_XANCPQ9PDF6, PUR4_XYLFAQ87DN2, PUR4_XYLFT
P38972, PUR4_YEASTQ1C5E7, PUR4_YERPAQ8ZCQ2, PUR4_YERPE
Q1CKD2, PUR4_YERPNQ667W1, PUR4_YERPSB0C6R3, PURL_ACAM1
A5G1X4, PURL_ACICJQ8UEB0, PURL_AGRFCA6TLS3, PURL_ALKMQ
B9JVW2, PURL_ALLAMB8JBS8, PURL_ANAD2Q2IHC1, PURL_ANADE
A7HIJ4, PURL_ANADFB4UIX7, PURL_ANASKB7GFT8, PURL_ANOFW
O67691, PURL_AQUAEO28339, PURL_ARCFUA8I8B0, PURL_AZOC5
C3PBN0, PURL_BACAAC3L532, PURL_BACACA0R8Z6, PURL_BACAH
Q81ZH2, PURL_BACANB7JM85, PURL_BACC0Q73EN5, PURL_BACC1
B7IUV3, PURL_BACC2C1EV63, PURL_BACC3B7H4T6, PURL_BACC4
B7HS32, PURL_BACC7A7GKH8, PURL_BACCNB9J1K5, PURL_BACCQ
Q81IQ3, PURL_BACCRQ63GT3, PURL_BACCZQ6HPA4, PURL_BACHK
Q65MS8, PURL_BACLDA9VRF1, PURL_BACMKA8FAM7, PURL_BACP2
P12042, PURL_BACSUA7Z249, PURL_BACVZA1UT47, PURL_BARBK
Q6G335, PURL_BARHEQ6FZI9, PURL_BARQUA9IVH5, PURL_BART1
B2IC83, PURL_BEII9Q89IC0, PURL_BRADUA5EMI1, PURL_BRASB
A4YRR9, PURL_BRASOB2S573, PURL_BRUA1Q2YNG6, PURL_BRUA2
A6X1J9, PURL_BRUA4Q57DR8, PURL_BRUABA9MAL4, PURL_BRUC2
C0RIH1, PURL_BRUMBQ8YGN1, PURL_BRUMEA5VQ15, PURL_BRUO2
B0CLG4, PURL_BRUSIQ8G183, PURL_BRUSUA8MCK2, PURL_CALMQ
Q8RBK5, PURL_CALS4A8Z6J5, PURL_CAMC1A7GYY9, PURL_CAMC5
A7I157, PURL_CAMHCA8FM09, PURL_CAMJ8A7H373, PURL_CAMJD
Q9PNY0, PURL_CAMJEA1VZU6, PURL_CAMJJQ5HUK4, PURL_CAMJR
B9KFP6, PURL_CAMLRQ3AD64, PURL_CARHZQ9A5F0, PURL_CAUVC
Q3J273, PURL_CERS4A4WQY3, PURL_CERS5B9KSY5, PURL_CERSK
Q11IV2, PURL_CHESBQ3ARU4, PURL_CHLCHQ3B3Y0, PURL_CHLL3
Q8KD17, PURL_CHLTEC3PIW7, PURL_CORA7Q9RHW9, PURL_CORAM
Q8FMM3, PURL_COREFA4QGY6, PURL_CORGBQ8NMI5, PURL_CORGL
Q4JXF0, PURL_CORJKQ6A6C0, PURL_CUTAKB8HRP1, PURL_CYAP4
Q9RXT4, PURL_DEIRAQ833Y9, PURL_ENTFAQ2NAT8, PURL_ERYLH
C4L299, PURL_EXISAQ2J4M9, PURL_FRACCQ5L3D2, PURL_GEOKA
C5D4I0, PURL_GEOSWA4IJX3, PURL_GEOTNQ7NIR9, PURL_GLOVI
Q5FNL0, PURL_GLUOXQ0BRI4, PURL_GRABCQ9KF57, PURL_HALH5
B9LT08, PURL_HALLTQ5V2D3, PURL_HALMAB0R4B5, PURL_HALS3
Q9HR49, PURL_HALSAQ18JI5, PURL_HALWDQ7VF52, PURL_HELHP
A8ABX6, PURL_IGNH4Q28QC2, PURL_JANSCQ5FIV1, PURL_LACAC
P35852, PURL_LACCAQ1G9F8, PURL_LACDAQ049L7, PURL_LACDB
A8YW85, PURL_LACH4Q9CFE8, PURL_LACLAQ9ZB06, PURL_LACLC
A2RJW3, PURL_LACLMQ02Y55, PURL_LACLSQ037U9, PURL_LACP3
Q88U25, PURL_LACPLQ38XW7, PURL_LATSSQ6ACC3, PURL_LEIXX
B0SB88, PURL_LEPBAQ04QS4, PURL_LEPBJQ053V5, PURL_LEPBL
B0ST16, PURL_LEPBPQ72PR5, PURL_LEPICQ8F6I3, PURL_LEPIN
Q03Y89, PURL_LEUMMQ1WU59, PURL_LIGS1B2GF74, PURL_LIMF3
A5VHT8, PURL_LIMRDB2G5B8, PURL_LIMRJQ92AN9, PURL_LISIN
C1KW68, PURL_LISMCQ71YP9, PURL_LISMFB8DDY8, PURL_LISMH
Q8Y6C1, PURL_LISMOA0AJM3, PURL_LISW6B9EAY8, PURL_MACCJ
A6UX13, PURL_META3Q8TIT6, PURL_METACQ46F25, PURL_METBF
Q58660, PURL_METJAQ8TY09, PURL_METKAQ8PYK1, PURL_METMA
A5UMW9, PURL_METS3A4YI68, PURL_METS5B8EPE8, PURL_METSB
Q2NEB6, PURL_METSTO27427, PURL_METTHP26500, PURL_METTM
A0B5C7, PURL_METTPQ2RGU5, PURL_MOOTAA0QAT1, PURL_MYCA1
B1MHY1, PURL_MYCA9P0A5T9, PURL_MYCBOA1KGT6, PURL_MYCBP
C1ALD8, PURL_MYCBTA4T7J3, PURL_MYCGIB8ZSV5, PURL_MYCLB
Q50023, PURL_MYCLEQ743F0, PURL_MYCPAA5U0J2, PURL_MYCTA
P9WHL6, PURL_MYCTOP9WHL7, PURL_MYCTUA1TFE0, PURL_MYCVP
Q3IQL3, PURL_NATPDQ1QMU2, PURL_NITHXA6Q3E8, PURL_NITSB
Q3ST22, PURL_NITWNQ5Z2C3, PURL_NOCFAA1SPT8, PURL_NOCSJ
B2IU46, PURL_NOSP7Q8YR06, PURL_NOSS1Q2G630, PURL_NOVAD
Q8ES96, PURL_OCEIHA1B943, PURL_PARDPA7HWB1, PURL_PARL1
Q7UA92, PURL_PARMWA8LCI3, PURL_PARS2Q4FLJ4, PURL_PELUB
A9BIH4, PURL_PETMOQ6KZR2, PURL_PICTOA3PA50, PURL_PROM0
A2BZA6, PURL_PROM1A8G1Z0, PURL_PROM2A2C5J9, PURL_PROM3
A2BTV9, PURL_PROM5Q31DI1, PURL_PROM9Q7VEK9, PURL_PROMA
Q7V9E5, PURL_PROMMQ7V3R5, PURL_PROMPA2BNC9, PURL_PROMS
Q46I59, PURL_PROMTA8F8I3, PURL_PSELTQ9UXW6, PURL_PYRAB
Q8ZZJ7, PURL_PYRAEA4WMV7, PURL_PYRARA3MXD4, PURL_PYRCJ
Q8U491, PURL_PYRFUO59621, PURL_PYRHOA1RQQ2, PURL_PYRIL
B1YBM5, PURL_PYRNVA9WV65, PURL_RENSMB3PPS1, PURL_RHIE6
Q2K7X0, PURL_RHIECQ1MG23, PURL_RHIJ3Q98NN7, PURL_RHILO
B5ZQU1, PURL_RHILWQ92PH7, PURL_RHIMEB9JFQ3, PURL_RHIR8
C0ZP44, PURL_RHOE4Q0S766, PURL_RHOJRC1ATA2, PURL_RHOOB
Q2ITQ2, PURL_RHOP2Q07R72, PURL_RHOP5Q6N9F2, PURL_RHOPA
Q218N3, PURL_RHOPBQ13AA1, PURL_RHOPSB3Q7H9, PURL_RHOPT
Q2RWI3, PURL_RHORTQ163V9, PURL_ROSDOQ5LS98, PURL_RUEPO
Q1GHL5, PURL_RUESTC3NH14, PURL_SACI1C3MQF3, PURL_SACI2
C3N674, PURL_SACI3C3MW31, PURL_SACI4C4KHN7, PURL_SACI6
C3NEN0, PURL_SACI7Q9UX24, PURL_SACS2Q2RZ77, PURL_SALRD
Q5WJ86, PURL_SHOC1Q9KH12, PURL_SINF1C3MD72, PURL_SINFN
A6U9L9, PURL_SINMWA7X0W1, PURL_STAA1A6U0N7, PURL_STAA2
Q2FI09, PURL_STAA3Q2FZJ0, PURL_STAA8A5IRV6, PURL_STAA9
Q2YX54, PURL_STAABQ5HH15, PURL_STAACA6QFS7, PURL_STAAE
P65900, PURL_STAAMP65901, PURL_STAANQ6GI15, PURL_STAAR
Q6GAE4, PURL_STAASA8Z1L1, PURL_STAATQ8NX92, PURL_STAAW
B9DQ38, PURL_STACTQ5HQA1, PURL_STAEQQ8CPN9, PURL_STAES
Q4L578, PURL_STAHJQ49WJ3, PURL_STAS1Q82FW4, PURL_STRAW
Q9RKK5, PURL_STRCOQ4J8F8, PURL_SULACQ30T55, PURL_SULDN
A6QAK6, PURL_SULNBQ970V6, PURL_SULTOQ67KF8, PURL_SYMTH
Q55041, PURL_SYNE7Q2JQL7, PURL_SYNJAQ2JI39, PURL_SYNJB
Q5N1Y6, PURL_SYNP6A5GHL4, PURL_SYNPWQ3B100, PURL_SYNS9
Q3ANP7, PURL_SYNSCP72644, PURL_SYNY3Q9HJA4, PURL_THEAC
Q47TL8, PURL_THEFYC5A4U6, PURL_THEGJQ5JFL7, PURL_THEKO
Q9X0X3, PURL_THEMAB0KBQ5, PURL_THEP3B0K3Q4, PURL_THEPX
B9KZ38, PURL_THERPC6A0I0, PURL_THESMQ72IH7, PURL_THET2
Q5SMH8, PURL_THET8Q8DIA7, PURL_THEVBQ97BD5, PURL_THEVO
Q3M6Z4, PURL_TRIV2Q83H66, PURL_TROW8Q83FE8, PURL_TROWT
Q7M9L5, PURL_WOLSUQ9REQ6, PURL_ZYMMOB0C7S1, PURQ_ACAM1
A6TLS2, PURQ_ALKMQQ2IG97, PURQ_ANADEB7GFT7, PURQ_ANOFW
O67190, PURQ_AQUAEO29008, PURQ_ARCFUC3PBM9, PURQ_BACAA
C3L531, PURQ_BACACA0R8Z5, PURQ_BACAHQ81ZH3, PURQ_BACAN
B7JM84, PURQ_BACC0Q73EN6, PURQ_BACC1B7IUV2, PURQ_BACC2
C1EV62, PURQ_BACC3B7H4T5, PURQ_BACC4B7HS31, PURQ_BACC7
A7GKH7, PURQ_BACCNB9J1K4, PURQ_BACCQQ81IQ4, PURQ_BACCR
Q63GT4, PURQ_BACCZQ6HPA5, PURQ_BACHKQ65MS9, PURQ_BACLD
A9VRF0, PURQ_BACMKA8FAM6, PURQ_BACP2P12041, PURQ_BACSU
A7Z248, PURQ_BACVZQ6G336, PURQ_BARHEQ6FZJ0, PURQ_BARQU
Q89IB6, PURQ_BRADUC0ZKC5, PURQ_BREBNQ2YNG3, PURQ_BRUA2
Q57DR5, PURQ_BRUABQ8YGN4, PURQ_BRUMEQ8G180, PURQ_BRUSU
Q8RBK6, PURQ_CALS4Q9PHZ7, PURQ_CAMJEQ3AD65, PURQ_CARHZ
Q9A5F3, PURQ_CAUVCQ3J4K2, PURQ_CERS4Q11IV0, PURQ_CHESB
Q3AS25, PURQ_CHLCHQ3B397, PURQ_CHLL3B3QMT1, PURQ_CHLP8
Q8KCS5, PURQ_CHLTEQ9RHX0, PURQ_CORAMQ8FMM2, PURQ_COREF
Q8NMI4, PURQ_CORGLQ4JXF1, PURQ_CORJKQ6A6B0, PURQ_CUTAK
Q3Z9H5, PURQ_DEHM1Q1J2B6, PURQ_DEIGDQ9RXT3, PURQ_DEIRA
Q833Y8, PURQ_ENTFAB1YJ04, PURQ_EXIS2C4L298, PURQ_EXISA
Q2J4N0, PURQ_FRACCQ5L3D3, PURQ_GEOKAC5D4H9, PURQ_GEOSW
A4IJX2, PURQ_GEOTNQ7NL01, PURQ_GLOVIQ5FNL1, PURQ_GLUOX
Q9KF58, PURQ_HALH5Q9HNU2, PURQ_HALSAQ18FM4, PURQ_HALWD
Q7VFQ4, PURQ_HELHPQ28PA2, PURQ_JANSCQ1IPG4, PURQ_KORVE
Q5FIV0, PURQ_LACACP35851, PURQ_LACCAB3WF98, PURQ_LACCB
Q1G9F7, PURQ_LACDAQ9CFE7, PURQ_LACLAQ9ZB07, PURQ_LACLC
Q037U8, PURQ_LACP3Q88U24, PURQ_LACPLQ38XW8, PURQ_LATSS
Q6ACD4, PURQ_LEIXXQ72UH6, PURQ_LEPICQ8F0I2, PURQ_LEPIN
Q1WU60, PURQ_LIGS1B2GF73, PURQ_LIMF3A5VHT7, PURQ_LIMRD
B2G5B7, PURQ_LIMRJQ92AN8, PURQ_LISINC1KW69, PURQ_LISMC
Q71YP8, PURQ_LISMFB8DDY7, PURQ_LISMHQ8Y6C0, PURQ_LISMO
A0AJM4, PURQ_LISW6B1HTV3, PURQ_LYSSCQ8TPF0, PURQ_METAC
Q468N4, PURQ_METBFQ59042, PURQ_METJAQ8TX85, PURQ_METKA
A4G010, PURQ_METM5A6VIG8, PURQ_METM7Q8PTB0, PURQ_METMA
Q6M0U0, PURQ_METMPQ2NF29, PURQ_METSTO26270, PURQ_METTH
A0B5C6, PURQ_METTPQ2RGU4, PURQ_MOOTAP65903, PURQ_MYCBO
O05756, PURQ_MYCLEQ743F9, PURQ_MYCPAP9WHL4, PURQ_MYCTO
P9WHL5, PURQ_MYCTUQ3IMR2, PURQ_NATPDQ1QMU3, PURQ_NITHX
Q3ST24, PURQ_NITWNQ5Z2C8, PURQ_NOCFAQ8YU79, PURQ_NOSS1
Q2G9J6, PURQ_NOVADQ8ES97, PURQ_OCEIHQ7U831, PURQ_PARMW
Q4FLJ5, PURQ_PELUBQ6L0V9, PURQ_PICTOQ31B97, PURQ_PROM9
Q7VC88, PURQ_PROMAQ7V834, PURQ_PROMMQ7V1S5, PURQ_PROMP
Q46LE9, PURQ_PROMTA8F8I4, PURQ_PSELTQ9UXW5, PURQ_PYRAB
Q8ZZJ9, PURQ_PYRAEQ8U492, PURQ_PYRFUO59619, PURQ_PYRHO
Q2K7X5, PURQ_RHIECQ1MG27, PURQ_RHIJ3Q98NN0, PURQ_RHILO
Q92PI1, PURQ_RHIMEQ0S774, PURQ_RHOJRQ2ITP9, PURQ_RHOP2
Q6N376, PURQ_RHOPAQ218N7, PURQ_RHOPBQ2RWI2, PURQ_RHORT
Q167J3, PURQ_ROSDOQ1AXB7, PURQ_RUBXDQ5LS78, PURQ_RUEPO
Q1GGM0, PURQ_RUESTQ9UX21, PURQ_SACS2Q2S567, PURQ_SALRD
Q5WJ87, PURQ_SHOC1Q1GVL0, PURQ_SPHALQ2FI10, PURQ_STAA3
Q2FZJ1, PURQ_STAA8Q2YX55, PURQ_STAABQ5HH16, PURQ_STAAC
P65904, PURQ_STAAMP99166, PURQ_STAANQ6GI16, PURQ_STAAR
Q6GAE5, PURQ_STAASQ8NX93, PURQ_STAAWQ5HQA2, PURQ_STAEQ
Q8CPP0, PURQ_STAESQ4L577, PURQ_STAHJQ49WJ2, PURQ_STAS1
Q82FW3, PURQ_STRAWQ9RKK6, PURQ_STRCOQ30TB2, PURQ_SULDN
Q67KF7, PURQ_SYMTHQ31Q18, PURQ_SYNE7Q2JWK2, PURQ_SYNJA
Q2JPK0, PURQ_SYNJBQ5N459, PURQ_SYNP6Q3AYR1, PURQ_SYNS9
Q3AII4, PURQ_SYNSCQ55843, PURQ_SYNY3Q9HIM1, PURQ_THEAC
Q5JFP4, PURQ_THEKOQ9X0X2, PURQ_THEMAB9KZ37, PURQ_THERP
Q72IH9, PURQ_THET2Q5SI57, PURQ_THET8Q8DGX5, PURQ_THEVB
Q97C36, PURQ_THEVOQ73MV2, PURQ_TREDEQ3MG53, PURQ_TRIV2
Q7M9X7, PURQ_WOLSUQ5NMA4, PURQ_ZYMMOO28338, PURS_ARCFU
P12049, PURS_BACSUQ58988, PURS_METJAO26271, PURS_METTH
O05755, PURS_MYCLEQ55842, PURS_SYNY3Q9X0X1, PURS_THEMA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.5.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-