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ENZYME

ENZYME entry: EC 6.3.5.3

Accepted Name
phosphoribosylformylglycinamidine synthase
Alternative Name(s)
FGAM synthase
FGAM synthetase
FGAR amidotransferase
FGARAT
formylglycinamide ribotide amidotransferase
phosphoribosylformylglycinamidine synthetase
Reaction catalysed
ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide <=> 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate
Cross-references
BRENDA6.3.5.3
EC2PDB6.3.5.3
ExplorEnz6.3.5.3
PRIAM enzyme-specific profiles6.3.5.3
KEGG Ligand Database for Enzyme Nomenclature6.3.5.3
IUBMB Enzyme Nomenclature6.3.5.3
IntEnz6.3.5.3
MEDLINEFind literature relating to 6.3.5.3
MetaCyc6.3.5.3
Rhea expert-curated reactions6.3.5.3
UniProtKB/Swiss-Prot
Q5E749, PUR4_ALIF1Q9M8D3, PUR4_ARATHQ19311, PUR4_CAEEL
Q47XX7, PUR4_COLP3Q54JC8, PUR4_DICDIP35421, PUR4_DROME
Q8XA46, PUR4_ECO57Q0TET1, PUR4_ECOL5Q8FF26, PUR4_ECOL6
P15254, PUR4_ECOLIQ1R8H7, PUR4_ECOUTQ4QME6, PUR4_HAEI8
P43847, PUR4_HAEINQ0I5H4, PUR4_HAES1Q2SK05, PUR4_HAHCH
O15067, PUR4_HUMANQ5QWY0, PUR4_IDILOQ65RJ7, PUR4_MANSM
Q1H2I8, PUR4_METFKQ5SUR0, PUR4_MOUSEQ1D9V4, PUR4_MYXXD
Q5F7J4, PUR4_NEIG1Q9JWC5, PUR4_NEIMAQ9JXK5, PUR4_NEIMB
Q9CLW4, PUR4_PASMUQ6D238, PUR4_PECASQ7N1Z4, PUR4_PHOLL
Q6LU24, PUR4_PHOPRQ48LX3, PUR4_PSE14Q15R69, PUR4_PSEA6
Q9HXN2, PUR4_PSEAEQ4KHS6, PUR4_PSEF5Q3KHL4, PUR4_PSEPF
Q88P16, PUR4_PSEPKQ886W6, PUR4_PSESMQ3IHZ2, PUR4_PSET1
Q4ZX02, PUR4_PSEU2Q8XYN6, PUR4_RALSOQ57LE6, PUR4_SALCH
Q5PIG8, PUR4_SALPAQ8Z4L6, PUR4_SALTIP74881, PUR4_SALTY
O14228, PUR4_SCHPOQ12PR7, PUR4_SHEDOQ085S1, PUR4_SHEFN
Q8EC57, PUR4_SHEONQ0HKU9, PUR4_SHESMQ0HX47, PUR4_SHESR
Q31XT0, PUR4_SHIBSQ32D15, PUR4_SHIDSQ3YYZ8, PUR4_SHISS
Q2NS22, PUR4_SODGMQ9KTN2, PUR4_VIBCHQ87RW0, PUR4_VIBPA
Q8DF81, PUR4_VIBVUQ7MN70, PUR4_VIBVYQ8PGR7, PUR4_XANAC
Q8PCQ7, PUR4_XANCPQ9PDF6, PUR4_XYLFAQ87DN2, PUR4_XYLFT
P38972, PUR4_YEASTQ1C5E7, PUR4_YERPAQ8ZCQ2, PUR4_YERPE
Q1CKD2, PUR4_YERPNQ667W1, PUR4_YERPSB0C6R3, PURL_ACAM1
A5G1X4, PURL_ACICJQ8UEB0, PURL_AGRFCB9JFQ3, PURL_AGRRK
B9JVW2, PURL_AGRVSQ5WJ86, PURL_ALKCKA6TLS3, PURL_ALKMQ
B8JBS8, PURL_ANAD2Q2IHC1, PURL_ANADEA7HIJ4, PURL_ANADF
B4UIX7, PURL_ANASKB7GFT8, PURL_ANOFWO67691, PURL_AQUAE
O28339, PURL_ARCFUA8I8B0, PURL_AZOC5C3PBN0, PURL_BACAA
C3L532, PURL_BACACA0R8Z6, PURL_BACAHQ81ZH2, PURL_BACAN
B7JM85, PURL_BACC0Q73EN5, PURL_BACC1B7IUV3, PURL_BACC2
C1EV63, PURL_BACC3B7H4T6, PURL_BACC4B7HS32, PURL_BACC7
A7GKH8, PURL_BACCNB9J1K5, PURL_BACCQQ81IQ3, PURL_BACCR
Q63GT3, PURL_BACCZQ6HPA4, PURL_BACHKQ65MS8, PURL_BACLD
A9VRF1, PURL_BACMKA8FAM7, PURL_BACP2P12042, PURL_BACSU
A7Z249, PURL_BACVZA1UT47, PURL_BARBKQ6G335, PURL_BARHE
Q6FZI9, PURL_BARQUA9IVH5, PURL_BART1B2IC83, PURL_BEII9
Q89IC0, PURL_BRADUA5EMI1, PURL_BRASBA4YRR9, PURL_BRASO
B2S573, PURL_BRUA1Q2YNG6, PURL_BRUA2A6X1J9, PURL_BRUA4
Q57DR8, PURL_BRUABA9MAL4, PURL_BRUC2C0RIH1, PURL_BRUMB
Q8YGN1, PURL_BRUMEA5VQ15, PURL_BRUO2B0CLG4, PURL_BRUSI
Q8G183, PURL_BRUSUA8MCK2, PURL_CALMQQ8RBK5, PURL_CALS4
A8Z6J5, PURL_CAMC1A7GYY9, PURL_CAMC5A7I157, PURL_CAMHC
A8FM09, PURL_CAMJ8A7H373, PURL_CAMJDQ9PNY0, PURL_CAMJE
A1VZU6, PURL_CAMJJQ5HUK4, PURL_CAMJRB9KFP6, PURL_CAMLR
Q3AD64, PURL_CARHZQ9A5F0, PURL_CAUVCQ3J273, PURL_CERS4
A4WQY3, PURL_CERS5B9KSY5, PURL_CERSKQ11IV2, PURL_CHESB
Q3ARU4, PURL_CHLCHQ3B3Y0, PURL_CHLL3Q8KD17, PURL_CHLTE
C3PIW7, PURL_CORA7Q9RHW9, PURL_CORAMQ8FMM3, PURL_COREF
A4QGY6, PURL_CORGBQ8NMI5, PURL_CORGLQ4JXF0, PURL_CORJK
Q6A6C0, PURL_CUTAKB8HRP1, PURL_CYAP4Q9RXT4, PURL_DEIRA
Q833Y9, PURL_ENTFAQ2NAT8, PURL_ERYLHC4L299, PURL_EXISA
Q2J4M9, PURL_FRACCA8LCI3, PURL_FRASNQ5L3D2, PURL_GEOKA
C5D4I0, PURL_GEOSWA4IJX3, PURL_GEOTNQ7NIR9, PURL_GLOVI
Q5FNL0, PURL_GLUOXQ0BRI4, PURL_GRABCQ9KF57, PURL_HALH5
B9LT08, PURL_HALLTQ5V2D3, PURL_HALMAB0R4B5, PURL_HALS3
Q9HR49, PURL_HALSAQ18JI5, PURL_HALWDQ7VF52, PURL_HELHP
A8ABX6, PURL_IGNH4Q28QC2, PURL_JANSCQ5FIV1, PURL_LACAC
P35852, PURL_LACCAQ1G9F8, PURL_LACDAQ049L7, PURL_LACDB
A8YW85, PURL_LACH4Q9CFE8, PURL_LACLAQ9ZB06, PURL_LACLC
A2RJW3, PURL_LACLMQ02Y55, PURL_LACLSQ037U9, PURL_LACP3
Q88U25, PURL_LACPLQ38XW7, PURL_LATSSQ6ACC3, PURL_LEIXX
B0SB88, PURL_LEPBAQ04QS4, PURL_LEPBJQ053V5, PURL_LEPBL
B0ST16, PURL_LEPBPQ72PR5, PURL_LEPICQ8F6I3, PURL_LEPIN
Q03Y89, PURL_LEUMMQ1WU59, PURL_LIGS1B2GF74, PURL_LIMF3
A5VHT8, PURL_LIMRDB2G5B8, PURL_LIMRJQ92AN9, PURL_LISIN
C1KW68, PURL_LISMCQ71YP9, PURL_LISMFB8DDY8, PURL_LISMH
Q8Y6C1, PURL_LISMOA0AJM3, PURL_LISW6B9EAY8, PURL_MACCJ
A6UX13, PURL_META3Q8TIT6, PURL_METACQ46F25, PURL_METBF
Q58660, PURL_METJAQ8TY09, PURL_METKAQ8PYK1, PURL_METMA
A5UMW9, PURL_METS3A4YI68, PURL_METS5B8EPE8, PURL_METSB
Q2NEB6, PURL_METSTO27427, PURL_METTHP26500, PURL_METTM
A0B5C7, PURL_METTPQ2RGU5, PURL_MOOTAA0QAT1, PURL_MYCA1
B1MHY1, PURL_MYCA9P0A5T9, PURL_MYCBOA1KGT6, PURL_MYCBP
C1ALD8, PURL_MYCBTA4T7J3, PURL_MYCGIB8ZSV5, PURL_MYCLB
Q50023, PURL_MYCLEQ743F0, PURL_MYCPAA5U0J2, PURL_MYCTA
P9WHL6, PURL_MYCTOP9WHL7, PURL_MYCTUA1TFE0, PURL_MYCVP
Q3IQL3, PURL_NATPDQ1QMU2, PURL_NITHXA6Q3E8, PURL_NITSB
Q3ST22, PURL_NITWNQ5Z2C3, PURL_NOCFAA1SPT8, PURL_NOCSJ
B2IU46, PURL_NOSP7Q8YR06, PURL_NOSS1Q2G630, PURL_NOVAD
Q8ES96, PURL_OCEIHA1B943, PURL_PARDPA7HWB1, PURL_PARL1
Q7UA92, PURL_PARMWQ4FLJ4, PURL_PELUBA9BIH4, PURL_PETMO
Q6KZR2, PURL_PICTOA3PA50, PURL_PROM0A2BZA6, PURL_PROM1
A8G1Z0, PURL_PROM2A2C5J9, PURL_PROM3A2BTV9, PURL_PROM5
Q31DI1, PURL_PROM9Q7VEK9, PURL_PROMAQ7V9E5, PURL_PROMM
Q7V3R5, PURL_PROMPA2BNC9, PURL_PROMSQ46I59, PURL_PROMT
A8F8I3, PURL_PSELTQ9UXW6, PURL_PYRABQ8ZZJ7, PURL_PYRAE
A4WMV7, PURL_PYRARA3MXD4, PURL_PYRCJQ8U491, PURL_PYRFU
O59621, PURL_PYRHOA1RQQ2, PURL_PYRILB1YBM5, PURL_PYRNV
A9WV65, PURL_RENSMB3PPS1, PURL_RHIE6Q2K7X0, PURL_RHIEC
Q9KH12, PURL_RHIFHQ1MG23, PURL_RHIL3Q98NN7, PURL_RHILO
B5ZQU1, PURL_RHILWQ92PH7, PURL_RHIMEC0ZP44, PURL_RHOE4
Q0S766, PURL_RHOJRC1ATA2, PURL_RHOOBQ2ITQ2, PURL_RHOP2
Q07R72, PURL_RHOP5Q6N9F2, PURL_RHOPAQ218N3, PURL_RHOPB
Q13AA1, PURL_RHOPSB3Q7H9, PURL_RHOPTQ2RWI3, PURL_RHORT
Q163V9, PURL_ROSDOQ5LS98, PURL_RUEPOQ1GHL5, PURL_RUEST
Q9UX24, PURL_SACS2Q2RZ77, PURL_SALRDC3MD72, PURL_SINFN
A6U9L9, PURL_SINMWA7X0W1, PURL_STAA1A6U0N7, PURL_STAA2
Q2FI09, PURL_STAA3Q2FZJ0, PURL_STAA8A5IRV6, PURL_STAA9
Q2YX54, PURL_STAABQ5HH15, PURL_STAACA6QFS7, PURL_STAAE
P65900, PURL_STAAMP65901, PURL_STAANQ6GI15, PURL_STAAR
Q6GAE4, PURL_STAASA8Z1L1, PURL_STAATQ8NX92, PURL_STAAW
B9DQ38, PURL_STACTQ5HQA1, PURL_STAEQQ8CPN9, PURL_STAES
Q4L578, PURL_STAHJQ49WJ3, PURL_STAS1Q82FW4, PURL_STRAW
Q9RKK5, PURL_STRCOQ4J8F8, PURL_SULACQ30T55, PURL_SULDN
C3N674, PURL_SULIAC4KHN7, PURL_SULIKC3MQF3, PURL_SULIL
C3MW31, PURL_SULIMC3NH14, PURL_SULINC3NEN0, PURL_SULIY
A6QAK6, PURL_SULNBQ970V6, PURL_SULTOQ67KF8, PURL_SYMTH
Q55041, PURL_SYNE7Q2JQL7, PURL_SYNJAQ2JI39, PURL_SYNJB
Q5N1Y6, PURL_SYNP6A5GHL4, PURL_SYNPWQ3B100, PURL_SYNS9
Q3ANP7, PURL_SYNSCP72644, PURL_SYNY3Q9HJA4, PURL_THEAC
Q47TL8, PURL_THEFYC5A4U6, PURL_THEGJQ5JFL7, PURL_THEKO
Q9X0X3, PURL_THEMAB0KBQ5, PURL_THEP3B0K3Q4, PURL_THEPX
B9KZ38, PURL_THERPC6A0I0, PURL_THESMQ72IH7, PURL_THET2
Q5SMH8, PURL_THET8Q8DIA7, PURL_THEVBQ97BD5, PURL_THEVO
Q3M6Z4, PURL_TRIV2Q83H66, PURL_TROW8Q83FE8, PURL_TROWT
Q7M9L5, PURL_WOLSUQ9REQ6, PURL_ZYMMOB0C7S1, PURQ_ACAM1
Q5WJ87, PURQ_ALKCKA6TLS2, PURQ_ALKMQQ2IG97, PURQ_ANADE
B7GFT7, PURQ_ANOFWO67190, PURQ_AQUAEO29008, PURQ_ARCFU
C3PBM9, PURQ_BACAAC3L531, PURQ_BACACA0R8Z5, PURQ_BACAH
Q81ZH3, PURQ_BACANB7JM84, PURQ_BACC0Q73EN6, PURQ_BACC1
B7IUV2, PURQ_BACC2C1EV62, PURQ_BACC3B7H4T5, PURQ_BACC4
B7HS31, PURQ_BACC7A7GKH7, PURQ_BACCNB9J1K4, PURQ_BACCQ
Q81IQ4, PURQ_BACCRQ63GT4, PURQ_BACCZQ6HPA5, PURQ_BACHK
Q65MS9, PURQ_BACLDA9VRF0, PURQ_BACMKA8FAM6, PURQ_BACP2
P12041, PURQ_BACSUA7Z248, PURQ_BACVZQ6G336, PURQ_BARHE
Q6FZJ0, PURQ_BARQUQ89IB6, PURQ_BRADUC0ZKC5, PURQ_BREBN
Q2YNG3, PURQ_BRUA2Q57DR5, PURQ_BRUABQ8YGN4, PURQ_BRUME
Q8G180, PURQ_BRUSUQ8RBK6, PURQ_CALS4Q9PHZ7, PURQ_CAMJE
Q3AD65, PURQ_CARHZQ9A5F3, PURQ_CAUVCQ3J4K2, PURQ_CERS4
Q11IV0, PURQ_CHESBQ3AS25, PURQ_CHLCHQ3B397, PURQ_CHLL3
B3QMT1, PURQ_CHLP8Q8KCS5, PURQ_CHLTEQ9RHX0, PURQ_CORAM
Q8FMM2, PURQ_COREFQ8NMI4, PURQ_CORGLQ4JXF1, PURQ_CORJK
Q6A6B0, PURQ_CUTAKQ3Z9H5, PURQ_DEHM1Q1J2B6, PURQ_DEIGD
Q9RXT3, PURQ_DEIRAQ833Y8, PURQ_ENTFAB1YJ04, PURQ_EXIS2
C4L298, PURQ_EXISAQ2J4N0, PURQ_FRACCQ5L3D3, PURQ_GEOKA
C5D4H9, PURQ_GEOSWA4IJX2, PURQ_GEOTNQ7NL01, PURQ_GLOVI
Q5FNL1, PURQ_GLUOXQ9KF58, PURQ_HALH5Q9HNU2, PURQ_HALSA
Q18FM4, PURQ_HALWDQ7VFQ4, PURQ_HELHPQ28PA2, PURQ_JANSC
Q1IPG4, PURQ_KORVEQ5FIV0, PURQ_LACACP35851, PURQ_LACCA
B3WF98, PURQ_LACCBQ1G9F7, PURQ_LACDAQ9CFE7, PURQ_LACLA
Q9ZB07, PURQ_LACLCQ037U8, PURQ_LACP3Q88U24, PURQ_LACPL
Q38XW8, PURQ_LATSSQ6ACD4, PURQ_LEIXXQ72UH6, PURQ_LEPIC
Q8F0I2, PURQ_LEPINQ1WU60, PURQ_LIGS1B2GF73, PURQ_LIMF3
A5VHT7, PURQ_LIMRDB2G5B7, PURQ_LIMRJQ92AN8, PURQ_LISIN
C1KW69, PURQ_LISMCQ71YP8, PURQ_LISMFB8DDY7, PURQ_LISMH
Q8Y6C0, PURQ_LISMOA0AJM4, PURQ_LISW6B1HTV3, PURQ_LYSSC
Q8TPF0, PURQ_METACQ468N4, PURQ_METBFQ59042, PURQ_METJA
Q8TX85, PURQ_METKAA4G010, PURQ_METM5A6VIG8, PURQ_METM7
Q8PTB0, PURQ_METMAQ6M0U0, PURQ_METMPQ2NF29, PURQ_METST
O26270, PURQ_METTHA0B5C6, PURQ_METTPQ2RGU4, PURQ_MOOTA
P65903, PURQ_MYCBOO05756, PURQ_MYCLEQ743F9, PURQ_MYCPA
P9WHL4, PURQ_MYCTOP9WHL5, PURQ_MYCTUQ3IMR2, PURQ_NATPD
Q1QMU3, PURQ_NITHXQ3ST24, PURQ_NITWNQ5Z2C8, PURQ_NOCFA
Q8YU79, PURQ_NOSS1Q2G9J6, PURQ_NOVADQ8ES97, PURQ_OCEIH
Q7U831, PURQ_PARMWQ4FLJ5, PURQ_PELUBQ6L0V9, PURQ_PICTO
Q31B97, PURQ_PROM9Q7VC88, PURQ_PROMAQ7V834, PURQ_PROMM
Q7V1S5, PURQ_PROMPQ46LE9, PURQ_PROMTA8F8I4, PURQ_PSELT
Q9UXW5, PURQ_PYRABQ8ZZJ9, PURQ_PYRAEQ8U492, PURQ_PYRFU
O59619, PURQ_PYRHOQ2K7X5, PURQ_RHIECQ1MG27, PURQ_RHIL3
Q98NN0, PURQ_RHILOQ92PI1, PURQ_RHIMEQ0S774, PURQ_RHOJR
Q2ITP9, PURQ_RHOP2Q6N376, PURQ_RHOPAQ218N7, PURQ_RHOPB
Q2RWI2, PURQ_RHORTQ167J3, PURQ_ROSDOQ1AXB7, PURQ_RUBXD
Q5LS78, PURQ_RUEPOQ1GGM0, PURQ_RUESTQ9UX21, PURQ_SACS2
Q2S567, PURQ_SALRDQ1GVL0, PURQ_SPHALQ2FI10, PURQ_STAA3
Q2FZJ1, PURQ_STAA8Q2YX55, PURQ_STAABQ5HH16, PURQ_STAAC
P65904, PURQ_STAAMP99166, PURQ_STAANQ6GI16, PURQ_STAAR
Q6GAE5, PURQ_STAASQ8NX93, PURQ_STAAWQ5HQA2, PURQ_STAEQ
Q8CPP0, PURQ_STAESQ4L577, PURQ_STAHJQ49WJ2, PURQ_STAS1
Q82FW3, PURQ_STRAWQ9RKK6, PURQ_STRCOQ30TB2, PURQ_SULDN
Q67KF7, PURQ_SYMTHQ31Q18, PURQ_SYNE7Q2JWK2, PURQ_SYNJA
Q2JPK0, PURQ_SYNJBQ5N459, PURQ_SYNP6Q3AYR1, PURQ_SYNS9
Q3AII4, PURQ_SYNSCQ55843, PURQ_SYNY3Q9HIM1, PURQ_THEAC
Q5JFP4, PURQ_THEKOQ9X0X2, PURQ_THEMAB9KZ37, PURQ_THERP
Q72IH9, PURQ_THET2Q5SI57, PURQ_THET8Q8DGX5, PURQ_THEVB
Q97C36, PURQ_THEVOQ73MV2, PURQ_TREDEQ3MG53, PURQ_TRIV2
Q7M9X7, PURQ_WOLSUQ5NMA4, PURQ_ZYMMOO28338, PURS_ARCFU
P12049, PURS_BACSUQ58988, PURS_METJAO26271, PURS_METTH
O05755, PURS_MYCLEQ55842, PURS_SYNY3Q9X0X1, PURS_THEMA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-