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ENZYME

ENZYME entry: EC 6.4.1.7

PURL: https://purl.expasy.org/enzyme/EC/6.4.1.7
Accepted Name
2-oxoglutarate carboxylase
Alternative Name(s)
carboxylating factor for ICDH
CFI
OGC
oxalosuccinate synthetase
Reaction catalysed
hydrogencarbonate + 2-oxoglutarate + ATP = (S)-oxalosuccinate + ADP + phosphate + H(+)
Comment(s)
  • It was originally thought that this enzyme was a promoting factor for the carboxylation of 2-oxoglutarate by EC 1.1.1.41, but this has since been disproved.
  • The product of the reaction is unstable and is quickly converted into isocitrate by the action of EC 1.1.1.41.
Cross-references
BRENDA6.4.1.7
EC2PDB6.4.1.7
ExplorEnz6.4.1.7
KEGG Ligand Database for Enzyme Nomenclature6.4.1.7
IUBMB Enzyme Nomenclature6.4.1.7
MEDLINEFind literature relating to 6.4.1.7
MetaCyc6.4.1.7
Rhea expert-curated reactions6.4.1.7
UniProtKB/Swiss-Prot
D3DJ41, 2OCL_HYDTTD3DJ42, 2OCS_HYDTT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-