ENZYME entry: EC 6.4.1.7
| Accepted Name |
|---|
| 2-oxoglutarate carboxylase.
|
| Alternative Name(s) |
|---|
| Carboxylating factor for ICDH. |
| CFI. |
| OGC. |
| Oxalosuccinate synthetase. |
| Reaction catalysed |
|---|
| ATP + 2-oxoglutarate + HCO(3)(-) <=> ADP + phosphate + oxalosuccinate |
| Cofactor(s) |
|---|
| Biotin; Mg(2+).
|
| Comment(s) |
|---|
- It was originally thought that this enzyme was a promoting factor for
the carboxylation of 2-oxoglutarate by EC 1.1.1.41, but this has
since been disproved.
- The product of the reaction is unstable and is quickly converted into
isocitrate by the action of EC 1.1.1.41.
|
| Cross-references |
|---|
| PROSITE | PDOC00676 ; PDOC50975 |
| BRENDA | 6.4.1.7 |
| EC2PDB | 6.4.1.7 |
| ExplorEnz | 6.4.1.7 |
| PRIAM enzyme-specific profiles | 6.4.1.7 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.4.1.7 |
| IUBMB Enzyme Nomenclature | 6.4.1.7 |
| IntEnz | 6.4.1.7 |
| MEDLINE | Find literature relating to 6.4.1.7 |
| MetaCyc | 6.4.1.7 |
| UniProtKB/Swiss-Prot |
|
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