ENZYME entry: EC 6.4.1.7
Accepted Name |
2-oxoglutarate carboxylase.
|
Alternative Name(s) |
Carboxylating factor for ICDH. |
CFI. |
OGC. |
Oxalosuccinate synthetase. |
Reaction catalysed |
ATP + 2-oxoglutarate + HCO(3)(-) <=> ADP + phosphate + oxalosuccinate |
Cofactor(s) |
Biotin; Mg(2+).
|
Comment(s) |
- It was originally thought that this enzyme was a promoting factor for
the carboxylation of 2-oxoglutarate by EC 1.1.1.41, but this has
since been disproved.
- The product of the reaction is unstable and is quickly converted into
isocitrate by the action of EC 1.1.1.41.
|
Cross-references |
PROSITE | PDOC00676 ; PDOC50975 |
BRENDA | 6.4.1.7 |
EC2PDB | 6.4.1.7 |
ExplorEnz | 6.4.1.7 |
PRIAM enzyme-specific profiles | 6.4.1.7 |
KEGG Ligand Database for Enzyme Nomenclature | 6.4.1.7 |
IUBMB Enzyme Nomenclature | 6.4.1.7 |
IntEnz | 6.4.1.7 |
MEDLINE | Find literature relating to 6.4.1.7 |
MetaCyc | 6.4.1.7 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.4.1.-
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