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ENZYME entry: EC 7.2.2.3

Accepted Name
P-type Na(+) transporter.
Alternative Name(s)
Na(+)-exporting ATPase.
Na(+)-transporting ATPase.
Sodium transport ATPase.
Sodium-exporting ATPase.
Sodium-translocating P-type ATPase.
Reaction catalysed
ATP + H(2)O + Na(+)(Side 1) <=> ADP + phosphate + Na(+)(Side 2)
Cofactor(s)
Mg(2+).
Comment(s)
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme from yeast is involved in the efflux of Na(+), with one ion being exported per ATP hydrolyzed.
  • Some forms can also export Li(+) ions.
  • Cf. EC 7.2.2.1 and EC 7.2.2.4.
  • Formerly EC 3.6.3.7.
Cross-references
PROSITEPDOC00139
BRENDA7.2.2.3
EC2PDB7.2.2.3
ExplorEnz7.2.2.3
PRIAM enzyme-specific profiles7.2.2.3
KEGG Ligand Database for Enzyme Nomenclature7.2.2.3
IUBMB Enzyme Nomenclature7.2.2.3
IntEnz7.2.2.3
MEDLINEFind literature relating to 7.2.2.3
MetaCyc7.2.2.3
UniProtKB/Swiss-Prot
P13587, ATN1_YEAST;  Q01896, ATN2_YEAST;  Q12691, ATN5_YEAST;  

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