ENZYME entry: EC 2.3.1.109

Accepted Name
Arginine N-succinyltransferase.
Alternative Name(s)
AOST.
Arginine and ornithine N(2)-succinyltransferase.
Arginine succinyltransferase.
AST.
Reaction catalysed
Succinyl-CoA + L-arginine <=> CoA + N(2)-succinyl-L-arginine
Comment(s)
  • Also acts on L-ornithine.
  • This is the first enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
Cross-references
BRENDA2.3.1.109
EC2PDB2.3.1.109
ExplorEnz2.3.1.109
PRIAM enzyme-specific profiles2.3.1.109
KEGG Ligand Database for Enzyme Nomenclature2.3.1.109
IUBMB Enzyme Nomenclature2.3.1.109
IntEnz2.3.1.109
MEDLINEFind literature relating to 2.3.1.109
MetaCyc2.3.1.109
UniProtKB/Swiss-Prot
A8AHD9, ASTA_CITK8;  A7ZML5, ASTA_ECO24;  B7USC8, ASTA_ECO27;  
B7MAV8, ASTA_ECO45;  B7L6M1, ASTA_ECO55;  P0AE38, ASTA_ECO57;  
B5YQ34, ASTA_ECO5E;  B7NT30, ASTA_ECO7I;  B7MVM6, ASTA_ECO81;  
B7M1F9, ASTA_ECO8A;  C4ZZA3, ASTA_ECOBW;  B1XGK8, ASTA_ECODH;  
A8A0T9, ASTA_ECOHS;  A1ABS8, ASTA_ECOK1;  Q0TH83, ASTA_ECOL5;  
Q8FH00, ASTA_ECOL6;  B1IPI3, ASTA_ECOLC;  P0AE37, ASTA_ECOLI;  
B7N583, ASTA_ECOLU;  B6IBG7, ASTA_ECOSE;  B1LDY4, ASTA_ECOSM;  
Q1RB46, ASTA_ECOUT;  A4W9J6, ASTA_ENT38;  B7LQ45, ASTA_ESCF3;  
Q7N2G8, ASTA_PHOLL;  P80357, ASTA_PSEAE;  B5F845, ASTA_SALA4;  
A9MFG1, ASTA_SALAR;  B5FJD7, ASTA_SALDC;  B5QWI9, ASTA_SALEP;  
B4TGE1, ASTA_SALHS;  B4T3Z5, ASTA_SALNS;  Q5PHB9, ASTA_SALPA;  
A9N277, ASTA_SALPB;  B5BA71, ASTA_SALPK;  B4TUC2, ASTA_SALSV;  
Q8Z6G0, ASTA_SALTI;  Q8ZPV1, ASTA_SALTY;  B2U3C9, ASTA_SHIB3;  
Q321N9, ASTA_SHIBS;  Q32G89, ASTA_SHIDS;  Q0T4V4, ASTA_SHIF8;  
Q83L52, ASTA_SHIFL;  Q3Z294, ASTA_SHISS;  A1JS43, ASTA_YERE8;  
Q1C8B0, ASTA_YERPA;  B2K295, ASTA_YERPB;  Q9ZC67, ASTA_YERPE;  
A9QZ62, ASTA_YERPG;  A4TJU6, ASTA_YERPP;  Q66B20, ASTA_YERPS;  
B1JMD2, ASTA_YERPY;  P80358, ASTG_PSEAE;  

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