- Responsible for the formation of archaea-specific sn-glycerol-1-
phosphate, the first step in the biosynthesis of polar lipids in
archaea.
- It is the enantiomer of sn-glycerol 3-phosphate, the form of
glycerophosphate found in bacteria and eukaryotes.
- The other enzymes involved in the biosynthesis of polar lipids in
archaea are EC 2.5.1.41 and EC 2.5.1.42, which together alkylate the
hydroxy groups of glycerol 1-phosphate to give unsaturated
archaetidic acid, which is acted upon by EC 2.7.7.67 to form CDP-
unsaturated archaeol.
- The final step in the pathway involves the addition of L-serine, with
concomitant removal of CMP, leading to the production of unsaturated
archaetidylserine.
- Activity of the enzyme is stimulated by K(+).
|
| UniProtKB/Swiss-Prot |
| Q9YER2, G1PDH_AERPE; | O28599, G1PDH_ARCFU; | Q9KBR3, G1PDH_BACHD; |
| Q65GC3, G1PDH_BACLD; | Q5WL08, G1PDH_BACSK; | P94527, G1PDH_BACSU; |
| A7Z7G4, G1PDH_BACVZ; | A8MC03, G1PDH_CALMQ; | A0RXV2, G1PDH_CENSY; |
| B3EYN8, G1PDH_GEOSE; | A4IP94, G1PDH_GEOTN; | B9LUA0, G1PDH_HALLT; |
| Q5V5G2, G1PDH_HALMA; | B0R3A6, G1PDH_HALS3; | Q9HS49, G1PDH_HALSA; |
| Q18JW6, G1PDH_HALWD; | A2BN26, G1PDH_HYPBU; | A8ABP9, G1PDH_IGNH4; |
| B1L7K1, G1PDH_KORCO; | A6UUD2, G1PDH_META3; | Q8TJU1, G1PDH_METAC; |
| Q0W4M8, G1PDH_METAR; | A7I9R4, G1PDH_METB6; | Q46FR7, G1PDH_METBF; |
| Q12X59, G1PDH_METBU; | Q2FPC7, G1PDH_METHJ; | Q58122, G1PDH_METJA; |
| Q8TW08, G1PDH_METKA; | A2ST19, G1PDH_METLZ; | A4FZY2, G1PDH_METM5; |
| A9A874, G1PDH_METM6; | A6VIL2, G1PDH_METM7; | Q8PZA4, G1PDH_METMA; |
| A3CX71, G1PDH_METMJ; | Q6M0P4, G1PDH_METMP; | B8GGP5, G1PDH_METPE; |
| A5UJW3, G1PDH_METS3; | A4YIZ1, G1PDH_METS5; | Q2NFL8, G1PDH_METST; |
| P72010, G1PDH_METTH; | A0B5P3, G1PDH_METTP; | A6URL4, G1PDH_METVS; |
| Q3ING6, G1PDH_NATPD; | A9A2U8, G1PDH_NITMS; | Q6L0R7, G1PDH_PICTO; |
| Q9V0V0, G1PDH_PYRAB; | Q8ZWP5, G1PDH_PYRAE; | A4WLW1, G1PDH_PYRAR; |
| A3MTM6, G1PDH_PYRCJ; | Q8U147, G1PDH_PYRFU; | O59144, G1PDH_PYRHO; |
| A1RV58, G1PDH_PYRIL; | B1YCY7, G1PDH_PYRNV; | Q9UXE7, G1PDH_SACS2; |
| A3DN28, G1PDH_STAMF; | Q4JB01, G1PDH_SULAC; | C3N5P0, G1PDH_SULIA; |
| C4KHB6, G1PDH_SULIK; | C3MQ22, G1PDH_SULIL; | C3MVE1, G1PDH_SULIM; |
| C3NHE5, G1PDH_SULIN; | C3NEA4, G1PDH_SULIY; | P58460, G1PDH_SULTO; |
| Q9HJ16, G1PDH_THEAC; | Q5JH91, G1PDH_THEKO; | A1RZJ9, G1PDH_THEPD; |
| C6A2E4, G1PDH_THESM; | Q979B1, G1PDH_THEVO; |
|