- Responsible for the formation of archaea-specific sn-glycerol-1-
phosphate, the first step in the biosynthesis of polar lipids in
archaea.
- It is the enantiomer of sn-glycerol 3-phosphate, the form of
glycerophosphate found in bacteria and eukaryotes.
- The other enzymes involved in the biosynthesis of polar lipids in
archaea are EC 2.5.1.41 and EC 2.5.1.42, which together alkylate the
hydroxy groups of glycerol 1-phosphate to give unsaturated
archaetidic acid, which is acted upon by EC 2.7.7.67 to form CDP-
unsaturated archaeol.
- The final step in the pathway involves the addition of L-serine, with
concomitant removal of CMP, leading to the production of unsaturated
archaetidylserine.
- Activity of the enzyme is stimulated by K(+).
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UniProtKB/Swiss-Prot |
Q9YER2, G1PDH_AERPE | Q5WL08, G1PDH_ALKCK | O28599, G1PDH_ARCFU |
Q65GC3, G1PDH_BACLD | P94527, G1PDH_BACSU | A7Z7G4, G1PDH_BACVZ |
A8MC03, G1PDH_CALMQ | A0RXV2, G1PDH_CENSY | B3EYN8, G1PDH_GEOSE |
A4IP94, G1PDH_GEOTN | Q9KBR3, G1PDH_HALH5 | B9LUA0, G1PDH_HALLT |
Q5V5G2, G1PDH_HALMA | B0R3A6, G1PDH_HALS3 | Q9HS49, G1PDH_HALSA |
Q18JW6, G1PDH_HALWD | A2BN26, G1PDH_HYPBU | A8ABP9, G1PDH_IGNH4 |
B1L7K1, G1PDH_KORCO | A6UUD2, G1PDH_META3 | Q8TJU1, G1PDH_METAC |
Q0W4M8, G1PDH_METAR | A7I9R4, G1PDH_METB6 | Q46FR7, G1PDH_METBF |
Q12X59, G1PDH_METBU | Q2FPC7, G1PDH_METHJ | Q58122, G1PDH_METJA |
Q8TW08, G1PDH_METKA | A2ST19, G1PDH_METLZ | A4FZY2, G1PDH_METM5 |
A9A874, G1PDH_METM6 | A6VIL2, G1PDH_METM7 | Q8PZA4, G1PDH_METMA |
A3CX71, G1PDH_METMJ | Q6M0P4, G1PDH_METMP | B8GGP5, G1PDH_METPE |
A5UJW3, G1PDH_METS3 | A4YIZ1, G1PDH_METS5 | Q2NFL8, G1PDH_METST |
P72010, G1PDH_METTH | A0B5P3, G1PDH_METTP | A6URL4, G1PDH_METVS |
Q3ING6, G1PDH_NATPD | A9A2U8, G1PDH_NITMS | Q6L0R7, G1PDH_PICTO |
Q9V0V0, G1PDH_PYRAB | Q8ZWP5, G1PDH_PYRAE | A4WLW1, G1PDH_PYRAR |
A3MTM6, G1PDH_PYRCJ | Q8U147, G1PDH_PYRFU | O59144, G1PDH_PYRHO |
A1RV58, G1PDH_PYRIL | B1YCY7, G1PDH_PYRNV | Q9UXE7, G1PDH_SACS2 |
A3DN28, G1PDH_STAMF | Q4JB01, G1PDH_SULAC | C3N5P0, G1PDH_SULIA |
C4KHB6, G1PDH_SULIK | C3MQ22, G1PDH_SULIL | C3MVE1, G1PDH_SULIM |
C3NHE5, G1PDH_SULIN | C3NEA4, G1PDH_SULIY | P58460, G1PDH_SULTO |
Q9HJ16, G1PDH_THEAC | Q5JH91, G1PDH_THEKO | A1RZJ9, G1PDH_THEPD |
C6A2E4, G1PDH_THESM | Q979B1, G1PDH_THEVO |
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